Severity: Warning
Message: fopen(/var/lib/php/sessions/ci_sessionhkah20ia4kqc0vf8btjpqdg7132h69f0): Failed to open stream: No space left on device
Filename: drivers/Session_files_driver.php
Line Number: 177
Backtrace:
File: /var/www/html/index.php
Line: 316
Function: require_once
Severity: Warning
Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)
Filename: Session/Session.php
Line Number: 137
Backtrace:
File: /var/www/html/index.php
Line: 316
Function: require_once
Severity: Warning
Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 197
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 197
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 271
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1057
Function: getPubMedXML
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3175
Function: GetPubMedArticleOutput_2016
File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 316
Function: require_once
Most gouty attacks are controlled with non-steroidal anti-inflammatory drugs (NSAIDs). To reduce side effects, appropriate use of short acting and long acting NSAID is necessary. Colchicine administration is limited to a small amount (0.5-2 mg) in the prodromal stage or within 24 hours of the gouty attack. Steroids are sometimes intra-articular administered to obtain rapid effects. Systemic liposteroid administration has been favorably performed for severe cases of repeated gouty attacks. Uric acid control should not be initiated until after the complete disappearance of the gouty attack. It is important to gradually decrease the urate accumulation and the uric acid level is controlled with a target value near the saturation concentration of urate in the joint fluid (6.0-7.0 mg/dl).
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