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Influences of gestational diabetes mellitus on the changes in the vaginal microbiota from antepartum to postpartum.
BMC Pregnancy Childbirth
March 2025
Department of Child Healthcare, Shenzhen Baoan Women's and Children's Hospital, Shenzhen, 518100, China.
Background: No consensus has yet been reached concerning whether there were significant differences in the vaginal microbiota according to maternal gestational diabetes mellitus (GDM) status. This study aimed to compare the vaginal microbiota of women with GDM and normal blood glucose before and after delivery and to prospectively evaluate the influence of GDM on the dynamic changes of vaginal microbiota from antepartum to postpartum.
Methods: This study included 20 GDM patients and 31 average pregnant women who gave birth at the Shenzhen Baoan Women's and Children's Hospital.
Characterization of the vaginal microbiota in women of childbearing age with different Nugent scores.
Microb Pathog
March 2025
Department of Clinical Laboratory, Nanping First Hospital Affiliated to Fujian Medical University, Nanping City, 353000, Fujian Province, China.
The present study investigated the richness and diversity of vaginal microbiota among a cohort of 60 childbearing-age women. The samples were classified into three groups: healthy control (HC), bacterial vaginosis (BV), and BV intermediate (BVI). The number of Operational Taxonomic Units (OTUs) per sample ranged from 50 to 212, with three groups having 469 (HC), 482 (BVI), and 456 (BV) OTUs.
View Article and Find Full Text PDFPrevalence of Amsel-defined bacterial vaginosis before and after transvaginal ultrasound with lubricant application.
Sex Transm Dis
March 2025
Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD.
Emerging evidence suggests a link between hyperosmolal vaginal lubricants and bacterial vaginosis (BV). In 80 patients undergoing transvaginal ultrasound (TVUS) with a standardized lubricant, we observed a significant increase in Amsel-defined BV 1-13 days post-TVUS compared to baseline, likely driven by heightened amine odor (OR: 5.88; 95% CI: 1.
View Article and Find Full Text PDFGetting Everyone on Board to Break the Cycle of Bacterial Vaginosis (BV) Recurrence: A Qualitative Study of Partner Treatment for BV.
Patient
March 2025
Monash University, School of Translational Medicine, Melbourne, VIC, Australia.
Introduction: Bacterial vaginosis (BV) is a common condition that affects the sexual wellbeing of women and other people with a vagina. Recurrence following individual treatment is frequent and exerts a cumulative burden over time. Researchers at the Melbourne Sexual Health Center have recently completed the first successful trial of male partner treatment (MPT) for BV, demonstrating the superior effectiveness of concurrent MPT in reducing recurrence.
View Article and Find Full Text PDFInvestigation of the female genital tract microbiome and its association with hydrosalpinx in women undergoing salpingectomy.
Arch Gynecol Obstet
March 2025
Department of Obstetrics and Gynecology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, POB 151, Beer Sheva, Israel.
Objective: To describe the microbiome of the vagina and fallopian tubes (FT) and its relation with hydrosalpinx.
Methods: Case-control study was conducted in women who underwent salpingectomy for hydrosalpinx (case) or other indications (controls). Samples were obtained during surgery and subjected to 16S rRNA amplicon sequencing, and analyses of alpha diversity and beta diversity measures were compared between sites and groups.
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