Direct projections from the medial vestibular nucleus to the posterior hypothalamic area was found in the macaque monkey by the anterograde and the retrograde tract-tracing methods. After injection of biotinylated dextran amine (BDA) into the ventrolateral part of the medial vestibular nucleus, anterogradely labeled axon terminals were seen bilaterally in the posterior hypothalamic area. After injection of wheat germ agglutinin-conjugated horseradish peroxidase (WGA-HRP) into the posterior hypothalamic area, retrogradely labeled neuronal cell bodies were observed bilaterally in the ventral part of the medial vestibular nucleus with a contralateral predominance.
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http://dx.doi.org/10.1016/s0304-3940(96)13206-7 | DOI Listing |
Front Neurol
January 2025
Oregon Hearing Research Center, Oregon Health & Science University, Portland, OR, United States.
Introduction: The brainstem vestibular nuclei neurons receive synaptic inputs from inner ear acceleration-sensing hair cells, cerebellar output neurons, and ascending signals from spinal proprioceptive-related neurons. The lateral (LVST) and medial (MVST) vestibulospinal (VS) tracts convey their coded signals to the spinal circuits to rapidly counter externally imposed perturbations to facilitate stability and provide a framework for self-generated head movements.
Methods: The present study describes the morphological characteristics of intraaxonally recorded and labeled VS neurons monosynaptically connected to the 8th nerve.
Exp Brain Res
January 2025
Department of Rehabilitation Medicine, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, 510080, China.
Vestibular dysfunction has been reported as a potential cause in adolescent idiopathic scoliosis (AIS). However, it remained unclear how stochastic galvanic vestibular stimulation (GVS) affected kinetic performance of patients with AIS. This study aimed to investigate the effect of stochastic GVS on ground reaction forces (GRF) measures during obstacle negotiation among patients with AIS.
View Article and Find Full Text PDFNeuroscience
January 2025
Department of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Diagnosis and Treatment of Major Neurological Diseases, National Key Clinical Department and Key Discipline of Neurology, No.58 Zhongshan Road 2, Guangzhou 510080, China. Electronic address:
Acute peripheral vestibular dysfunction is associated with a variety of postural and balance disturbances. Vestibular rehabilitation training (VRT) is widely acknowledged as an effective intervention for promoting vestibular compensation. Nevertheless, the broader implementation of early VRT is hindered by an incomplete understanding of its neurobiological mechanisms.
View Article and Find Full Text PDFGait Posture
December 2024
School of Health and Exercise Sciences, The University of British Columbia Okanagan, Kelowna, British Columbia, Canada. Electronic address:
Background: To maintain standing balance, vestibular cues are processed and integrated with other sensorimotor signals to produce appropriate motor adjustments. Whole-body vestibular-driven postural responses are context-dependent and transformed based upon head and foot posture. Previous reports indicate the importance of intrinsic foot muscles during standing, but it is unclear how vestibular-driven responses of these muscles are modulated by alterations in stability and head posture.
View Article and Find Full Text PDFNeuroradiology
December 2024
Department of Neuroimaging and Interventional Radiology, National Institute of Mental Health and Neurosciences, Bengaluru, India.
Purpose: Objective information about the central auditory pathways in vestibular schwannoma can guide strategies for hearing rehabilitation and prognostication. This study aims to generate this information using diffusion tensor imaging (DTI).
Methods: This is a prospective observational single center study including 35 patients with vestibular schwannoma and 40 controls.
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