The effects of sodium nitrate on the activity of digestive enzymes in mucosal and submucosal layers of the small intestine as well as in liver and kidney were studied in the growing rats maintained on either standard or protein-free diets. The enzyme systems were more sensitive in the growing rats to protein deprivation than in adult animals. However, the digestive enzymes were more resistant against nitrate intoxication in the growing rats.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Rats and mice rapidly update timed behaviors.
Anim Cogn
January 2025
Neuroscience Department, Oberlin College, 173 Lorain St, Oberlin, OH, USA.
Keeping track of time intervals is a crucial aspect of behavior and cognition. Many theoretical models of how the brain times behavior make predictions for steady-state performance of well-learned intervals, but the rate of learning intervals in these models varies greatly, ranging from one-shot learning to learning over thousands of trials. Here, we explored how quickly rats and mice adapt to changes in interval durations using a serial fixed-interval task.
View Article and Find Full Text PDFErgothioneine improves healthspan of aged animals by enhancing cGPDH activity through CSE-dependent persulfidation.
Cell Metab
January 2025
Leibniz Institute for Analytical Sciences, ISAS e.V., Dortmund, Germany; School of Molecular Biosciences, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK. Electronic address:
Ergothioneine (ET), a dietary thione/thiol, is receiving growing attention for its possible benefits in healthy aging and metabolic resilience. Our study investigates ET's effects on healthspan in aged animals, revealing lifespan extension and enhanced mobility in Caenorhabditis elegans, accompanied by improved stress resistance and reduced age-associated biomarkers. In aged rats, ET administration enhances exercise endurance, muscle mass, and vascularization, concomitant with higher NAD levels in muscle.
View Article and Find Full Text PDFEndothelial characteristics of cardiac stem cell antigen-1 expressing cells and their relevance to right ventricular adaptation.
Can J Physiol Pharmacol
January 2025
Dalhousie University, Department of Physiology and Biophysics, Halifax, Canada;
A growing body of evidence suggest that the stem cell antigen-1 expressing (Sca-1) cells in the heart may be the cardiac endothelial stem/progenitor cells. Their endothelial cell (EC) functions, and their role in RV physiology and pathophysiology of right heart failure (RHF) remains poorly defined. This study investigated EC characteristics of rat cardiac Sca-1 cells, assessed spatial distribution and studied changes in Sca1 cells during RV remodelling in monocrotaline (MCT) model of pulmonary hypertension and RV remodeling.
View Article and Find Full Text PDFStandardized pipelines support and facilitate integration of diverse datasets at the Rat Genome Database.
Database (Oxford)
January 2025
Rat Genome Database, Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, United States.
The Rat Genome Database (RGD) is a multispecies knowledgebase which integrates genetic, multiomic, phenotypic, and disease data across 10 mammalian species. To support cross-species, multiomics studies and to enhance and expand on data manually extracted from the biomedical literature by the RGD team of expert curators, RGD imports and integrates data from multiple sources. These include major databases and a substantial number of domain-specific resources, as well as direct submissions by individual researchers.
View Article and Find Full Text PDFFoliar spraying with zinc oxide nanoparticles enhances the anti-osteoporotic efficacy of the fruit extracts of L. by stimulating silybin production.
Front Plant Sci
January 2025
Department of Biological Sciences, College of Science, King Faisal University, Al-Ahsa, Saudi Arabia.
Introduction: is a medicinal plant that produces silymarin, which has been demonstrated to possess antiviral, anti-neurodegenerative, and anticancer activities. Silybin (A+B) are two major hepatoprotective flavonolignans produced predominantly in fruits. Several attempts have been made to increase the synthesis of silymarin, or its primary components, silybin (A+B).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!