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Burned-out testicular germ cell tumour presenting as acute inferior vena cava syndrome.
BMJ Case Rep
November 2020
Radiology, London North West University Healthcare NHS Trust, Harrow, London, UK.
Germ cell tumours (GCT) are the most common testicular neoplasms, seen mainly in young adults. Rarely they can affect extragonadal tissues, either as primary tumours or as metastases, most commonly to retroperitoneal lymph nodes. A 'burned-out' testicular tumour is a metastatic GCT with a relatively occult primary testicular tumour, which has histologically spontaneously regressed.
View Article and Find Full Text PDFImmature Teratoma of the Palm: A Rare Site of Presentation.
Cureus
September 2020
Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, IND.
Extragonadal teratomas in adults are an extremely rare entity. Teratomas may be mature or immature and are characterized by their midline presentation. We are presenting here a case report of immature teratoma of the palm in a 35-year-old female.
View Article and Find Full Text PDFExtragonadal germ cell tumors: Not just a matter of location. A review about clinical, molecular and pathological features.
Cancer Med
November 2019
Pathology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania "L. Vanvitelli", Naples, Italy.
Extragonadal germ cell tumors (EGGCTs) are uncommon neoplasms, which arise in anatomical locations other than gonads. The pathogenesis of these neoplasms is still poorly understood and it is a matter of debate if they really represent extragondal primary neoplasms or rather extragondal metastasis from occult gonadal neoplasms. The actual observations suggest that EGGCTs represent a unique entity, so their biology and behavior are substantially different from gonadal counterparts.
View Article and Find Full Text PDFTesticular Microlithiasis in the Setting of Primary Extragonadal Germ Cell Tumor: A Case Series.
Ultrasound Q
March 2017
*Department of Imaging Sciences and †Department of Pathology and Laboratory Medicine, University of Rochester Medical Center School of Medicine and Dentistry, Rochester, NY.
The clinical significance of testicular microlithiasis (TM) in patients with primary extragonadal germ cell tumor (EGCT) is not well understood. When EGCT is suspected, sonographic and physical examination of the testicles should be performed to evaluate for testicular lesion or atrophy; negative testicular ultrasound with current technology virtually excludes the possibility of occult primary lesion. Although EGCTs are known to be associated with elevated level of serum tumor markers, the utility of tumor markers in the presence of TM is not well understood.
View Article and Find Full Text PDFIntroduction: Primary extragonadal seminomas are rare tumors. There have been only a few cases of the primary retroperitoneal seminomas reported in the literature up to date.
Case Report: We reported a 56-year-old man with giant primary retroperitoneal seminoma presented with the enlargement of the left side of the abdomen and deep venous thrombosis of the left leg.
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