[Acidosis in severe acute asthma].

Presse Med

Service de Réanimation et Médecine d'Urgence, Hôpital Boucicaut, Paris.

Published: October 1996

On admission to intensive care units, the acid-base profile in acute severe asthma appears to be more diverse than previously. Especially a mixed or less frequently metabolic acidosis is eventually observed, which is not always caused by elevated lactate. On the other hand, hyperlactatemia is actually rather common, not necessarily accompanied by acidosis. This finding is as a rule related to massive doses of beta 2 adrenergic agents given parenterally: subsequent elevated lactate is in no way a marker of cellular hypoxia and has no pejorative meaning in this event. Hypercapnia with severe respiratory acidosis implies less and less mechanical ventilation; however, when mandatory, it has to be carried out using permissive hypercapnia, giving more favorable outcome while lowering side-effects.

Download full-text PDF

Source

Publication Analysis

Top Keywords

elevated lactate
8
[acidosis severe
4
severe acute
4
acute asthma]
4
asthma] admission
4
admission intensive
4
intensive care
4
care units
4
units acid-base
4
acid-base profile
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!