We present a case where rocuronium 80 mg (3 x ED95) was used in a rapid sequence induction in a 80-kg pregnant patient with an open eye injury. The patient was also receiving magnesium 2 g h-1 i.v. for preterm labour. The expected duration for neuromuscular block of rocuronium in the absence of magnesium would be approximately 53 min; with infusion of magnesium, the duration of neuromuscular block was prolonged four-fold (215 min). It is important to remember that magnesium potentiates the effects of all non-depolarizing neuromuscular blocking agents, including rocuronium.
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http://dx.doi.org/10.1093/bja/77.5.669 | DOI Listing |
JMIR Hum Factors
January 2025
Women's Health Research Institute, Vancouver, BC, Canada.
Background: Digital health innovations provide an opportunity to improve access to care, information, and quality of care during the perinatal period, a critical period of health for mothers and infants. However, research to develop perinatal digital health solutions needs to be informed by actual patient and health system needs in order to optimize implementation, adoption, and sustainability.
Objective: Our aim was to co-design a research agenda with defined research priorities that reflected health system realities and patient needs.
Sex Health
January 2025
Griffith University School of Applied Psychology, Griffith University, Mount Gravatt, Qld 4122, Australia.
Non-directive pregnancy options counselling (POC) is a core component of comprehensive reproductive health care for pregnant people wanting support in making a pregnancy outcome decision. Approximately one quarter of people with unintended pregnancies and people seeking abortion care seek POC. This study synthesises global evidence on access to and characteristics of quality non-directive POC.
View Article and Find Full Text PDFSouth Med J
February 2025
the Department of Public Health Sciences.
Objectives: Sickle cell disease (SCD), which disproportionately affects minorities, increases complications during pregnancy. Severe maternal mortality is increased in women with SCD, including morbidity related to the disease and other nondisease-related complications. It also can have devastating complications for fetuses, with increases in premature birth and low birth weight.
View Article and Find Full Text PDFJ Trauma Acute Care Surg
January 2025
From the Division of Acute Care Surgery, Department of Surgery (M.J.A., V.C., E.L., N.K., M.J.M., K.I., K. Matsushima), Los Angeles General Medical Center, and Department of Obstetrics and Gynecology (K. Matsuo), University of Southern California, Los Angeles, California.
Background: Adhesive small bowel obstruction (ASBO) is a rare, nonobstetrical abdominal emergency. Optimal management of ASBO during pregnancy remains unknown. This study analyzes management trends and outcomes of pregnant patients with ASBO in the United States.
View Article and Find Full Text PDFFront Public Health
January 2025
Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA, United States.
Introduction: Nutrition during pregnancy significantly impacts maternal and birth outcomes. A key factor contributing to the rise in adverse maternal and birth outcomes is poor nutrition. Produce prescription programs have the potential to address pregnancy-related adverse outcomes such as hypertensive disorders and gestational diabetes, but scientific evidence is limited.
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