Purpose: To report rapidly progressive rhino-orbitocerebral mucormycosis in a 47-year-old woman with both diabetes mellitus and the acquired immunodeficiency syndrome (AIDS).
Method: Case report including postmortem examination of the eyes, orbit, and brain of a patient with rhino-orbitocerebral mucormycosis, diabetes mellitus, and AIDS.
Results: Invasion by hyphae of the Rhizopus species produced an occlusive vasculitis and massive infarction of the optic chiasm. Fungal organisms were discovered in multiple granulomata of the optic nerve.
Conclusion: Infarction at the optic chiasm probably caused sudden blindness in this patient.
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| http://dx.doi.org/10.1016/s0002-9394(14)70392-7 | DOI Listing |
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