AI Article Synopsis
- The kidneys play a crucial role in protein metabolism, and the study uses disc electrophoresis to analyze urinary proteins.
- This method allows for the separation of proteins by molecular weight, helping to distinguish between different types of kidney diseases, specifically those affecting the glomerulus and the tubules.
- While effective, the time-intensive nature of this methodology means it isn't suitable for routine clinical use at this time.
Article Abstract
After introductory observations on the role of the kidney in protein metabolism, the methodology and results of disc electrophoresis on polyacrylamide, using detergents, are discussed. Separation of urinary proteins according to molecular weight permits the differentiation of kidney diseases into those of the glomerulus and of the tubules. Proteinurias of prerenal and postrenal origin are also differentiated. Owing to the considerable time involved, this methodology cannot at present be introduced for routine purposes.
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