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Objectives: To review current approaches to primary prevention of lung cancer and to screening for precarcinogenic or preclinical asymptomatic disease.
Data Sources: Research studies, review articles, and government reports relating to prevention of lung cancer and strategies for smoking cessation.
Conclusions: Because almost 90% of lung cancer cases can be attributed to tobacco, reduction of smoking is the appropriate focus of lung cancer prevention efforts. Lung cancer chemoprevention remains an experimental approach and large scale screening for lung cancer is of limited value.
Implications For Nursing Practice: Nurses are in a strategic position to prevent smoking initiation and to influence successful smoking cessation through education, information on the multiple modalities to assist behavioral change, and ongoing reinforcement.
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http://dx.doi.org/10.1016/s0749-2081(96)80024-6 | DOI Listing |
Respirology
March 2025
Centre for Research Excellence in Pulmonary Fibrosis, Camperdown, New South Wales, Australia.
Interstitial lung abnormalities (ILAs) represent radiological entities that comprise changes compatible with an interstitial process, occurring in individuals not suspected to have interstitial lung disease (ILD). The prevalence of ILAs ranges from 2.5% to 16.
View Article and Find Full Text PDFBMJ Glob Health
March 2025
Family Medicine and Community Health, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.
Purpose: This study longitudinally assessed the quality of life (QoL) in patients who completed chemoradiation (CRT) for cervical cancer in Botswana and compared the QoL for those living with and without HIV infection.
Methods: Patients with cervical cancer recommended for curative CRT were enrolled from August 2016 to February 2020. The European Organisation for Research and Treatment of Cancer Core Quality-of-Life (QLQ-C30) and cervical cancer-specific (QLQ-Cx24) questionnaires, translated into Setswana, were used to assess the QoL of patients prior to treatment (baseline), at the end of treatment (EOT) and in 3 month intervals post-treatment for 2 years, and statistical analyses were performed.
Joint Bone Spine
March 2025
Sorbonne Université, AP-HP, Département de médecine interne et Immunologie Clinique, Groupe Hospitalier Pitié Salpêtrière, Paris, France.
Introduction: Antinuclear antibodies (ANA) exhibit diverse specificities and are crucial biomarkers in autoimmune disease assessment. Among ANA, anti-centromere protein-F (CENP-F) antibodies have garnered interest due to their association with malignancies. This study aims to characterize the clinical and biological profiles of a large cohort of anti-CENP-F positive patients and evaluate associated diagnoses.
View Article and Find Full Text PDFCancer Lett
March 2025
Department of Thoracic Surgery, Affiliated Hospital 2 of Nantong University, Nantong First People's Hospital, Nantong 226001, China. Electronic address:
Non-small cell lung cancer (NSCLC) is acknowledged as the primary subtype of lung cancer. The Warburg effect, marked by elevated glucose consumption and lactate fermentation, is a prevalent characteristic of NSCLC. The mechanisms by which circRNA mediates the regulation of the Warburg effect and immune evasion in NSCLC remain unclear.
View Article and Find Full Text PDFEur J Pharmacol
March 2025
Department of Pharmacology & Toxicology, National Institute of Pharmaceutical Education & Research, Hajipur, Bihar, India. Electronic address:
Lung cancer (LC) remains the foremost cause of cancer-related mortality across the globe. Non-small cell lung cancer (NSCLC) is a type of LC that exhibits significant heterogeneity at histological and molecular levels. Genetic alterations in upstream signaling molecules activate cascades affecting apoptosis, proliferation, and differentiation.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!