[Lymphoproliferative pathology of the genitourinary tract. Report of 6 cases and review of the literature].

Objectives: Six cases of genitourinary lymphoma are described and the literature reviewed.

Methods/results: The cases had the following histopathological diagnosis: 1 small and large cell non-Hodgkin lymphoma (NHL) of the renal pelvis, 2 high grade centroblastic testicular NHL; 1 centroblastic-centroid bladder NHL, 1 lymphoplasmocytoid bladder NHL and 1 low grade NHL of the prostate. All but the prostatic lymphoma were primary. Treatment was by nephrectomy and chop polychemotherapy (PCT) for the renal pelvis NHL, orchiectomy for the 2 testicular NHLs (one case also received radiotherapy), chop PCT for the bladder NHLs and PCT for the prostatic NHL. Three patients have died: the patient with renal pelvis NHL, centroblastic-centroid bladder NHL and the patient with prostatic NHL.

Conclusions: Although these tumors are rare, they should be suspected in patients with lymphoma, elderly men with a testicular mass, patients with a large bladder compressing/infiltrating mass and in the immunnodepressed patients. A preoperative histopathological diagnosis must be made before performing radical surgery.