Twelve mycobacterial antigens were compared for induction of gamma interferon (IFN-gamma) secretion by human blood mononuclear cells of patients with leprosy. Fractionated Mycobacterium leprae antigens containing cell wall proteins or cytosolic and membrane proteins induced good IFN-gamma responses in tuberculoid leprosy patients. Lipoarabinomannan from M. tuberculosis Erdman and M. leprae mycolylarabinogalactan peptidoglycan were the poorest IFN-gamma inducers.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC174386 | PMC |
| http://dx.doi.org/10.1128/iai.64.10.4385-4389.1996 | DOI Listing |
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