The effect of cold ambient temperature on the energy cost and thermoregulation during exercise was studied in 18 male Sprague-Dawley rats accustomed to running for 2 weeks. For measuring T(b) and ensuring an unrestrained exercise performance, the rats were implanted with intraperitoneal telemetric radio transmitters. The rats ran at three submaximal exercise intensities (10, 15 and 20 m.min-1) at different T(a) values (22 degrees, 0 degree, -10 degrees and -20 degrees C) for 30 min. VO2 and Tb were continuously measured. During exercise at 0 degree C a 100% substitution of thermoregulatory heat production by exercise thermogenesis was observed. At T(a) values below 0 degree C the physical strain of exercise increased considerably: Vo2 increased 34-61% at -10 degrees C and 51% at -20 degrees C compared to the corresponding exercise intensity at T(a) 22 degrees C. A partial substitution of thermoregulatory heat production by exercise thermogenesis was observed in the cold. At -10 degrees C the cost for thermoregulation during exercise was 28% and at -20 degrees C 31% lower than at rest at the corresponding T(a) values. The rat could not maintain normal Tb during exercise below 0 degrees C. The T(b) dropped 1.5-1.8 degrees C at -10 degrees C and 2.5 degrees C at -20 degrees C. It is concluded that exercising below 0 degree C at submaximal levels (below 50% of VO2max) partially substitutes for thermoregulatory costs but is thermally unfavorable for the small-sized rat.
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http://dx.doi.org/10.1016/0300-9629(95)02088-8 | DOI Listing |
JAMA Netw Open
January 2025
Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego.
Importance: The degree that in-home cannabis smoking can be detected in the urine of resident children is unclear.
Objective: Test association of in-home cannabis smoking with urinary cannabinoids in children living at home.
Design, Setting, And Participants: This cross-sectional study used baseline data from Project Fresh Air, a 2012-2016 randomized clinical trial to reduce fine particulate matter levels.
J Xenobiot
December 2024
Institute of Natural Resources and Agrobiology of Seville, Spanish National Research Council (IRNAS-CSIC), 41012 Seville, Spain.
Ibuprofen (IBP) is one of the most consumed drugs in the world. It is only partially removed in wastewater treatment plants (WWTPs), being present in effluent wastewater and sewage sludge, causing the widespread introduction of IBP as an emergent xenobiotic in different environmental compartments. This study describes the use of CSW11, recently described as an IBP degrader, through bioaugmentation processes for the removal of IBP from water under different conditions (additional carbon sources, various concentrations of glucose and IBP).
View Article and Find Full Text PDFClocks Sleep
December 2024
Institute of Physics, Saratov State University, Astrahanskaia, 83, Saratov 410012, Russia.
This study involved 72 volunteers divided into two groups according to the apnea-hypopnea index (AHI): AHI>15 episodes per hour (ep/h) (main group, n=39, including 28 men, median AHI 44.15, median age 47), 0≤AHI≤15ep/h (control group, n=33, including 12 men, median AHI 2, median age 28). Each participant underwent polysomnography with a recording of 19 EEG channels.
View Article and Find Full Text PDFAnn Surg
January 2025
Division of Surgical Oncology, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Objective: To investigate whether tangential versus segmental portomesenteric venous resection (PVR) impacts surgical and oncological outcome in patients undergoing pancreatoduodenectomy for pancreatic cancer with portomesenteric vein (PMV) involvement.
Summary Background Data: Current comparative studies on tangential versus segmental PVR as part of pancreatoduodenectomy for pancreatic cancer include all degrees of PMV involvement, including cases where tangential PVR may not be a feasible approach, limiting the clinical applicability.
Methods: International retrospective study in 10 centers from 5 countries, including all consecutive patients after pancreatoduodenectomy with PVR for pancreatic cancer with ≤180° PMV involvement on cross-sectional imaging at diagnosis (2014-2020).
J Am Heart Assoc
January 2025
Department of Medicine, Division of Cardiology Emory University School of Medicine Atlanta GA USA.
Background: Acute psychological stress may induce physiological changes predisposing individuals to adverse health outcomes through hemodynamic and vascular effects. We studied the association between the aggregated stress-induced changes in hemodynamic and vascular function tests with adverse cardiovascular outcomes in patients with coronary artery disease, after adjusting for sociodemographic and clinical factors.
Methods And Results: Individuals with stable coronary artery disease from 2 prospective cohort studies were studied.
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