The aim of this research was to analyse variations in voided volumes and duration and time of voiding during daily activities on a physiological basis, and to explore the possible diagnostic value of the associated parameters. A small electronic device was developed to accurately measure voided urine volumes in healthy volunteers during consecutive periods of two to three weeks. In subsequent analysis, the voided volumes were related to the time interval between voidings and the duration of voiding. Three parameters could be identified that quantify different aspects of bladder capacity (modal volume, maximum volume and a threshold volume in the relation between average flow-rate and voided volume). By relating voided volumes to the time interval between voidings the circadian rhythm in urine production was detected.
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http://dx.doi.org/10.3109/00365599609182302 | DOI Listing |
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