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Splanchnic vein thrombosis: management for the thrombosis specialist.
J Thromb Haemost
October 2024
Division of Hematology and Hematologic Malignancies, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA. Electronic address:
Splanchnic vein thrombosis (SpVT) is an uncommon site of venous thrombosis that is associated with complications including portal hypertension and hepatic dysfunction. The evaluation and management of this patient population has evolved in recent years, but there are limited data from clinical trials to guide management. Given the various acquired and biologic risk factors leading to the development of SpVT and the potential complications that can arise from it, input from a multidisciplinary team can be valuable in managing such patients, including thrombosis specialists or hematologists, gastroenterologists or hepatologists, interventional radiologists, and surgeons.
View Article and Find Full Text PDFPortal Vein Thrombosis in COVID-19: An Underdiagnosed Disease?
J Clin Med
September 2024
Department of Gastroenterology and Hepatology, Hospital Universitario Puerta de Hierro Majadahonda, 28222 Madrid, Spain.
Multiple studies have linked COVID-19 to a higher incidence of thromboembolic disorders. However, the association of COVID-19 with other potentially life-threatening complications, such as splanchnic vein thrombosis, is less well understood. This study aims to assess the prevalence, patient characteristics, clinical presentation, and outcomes of patients with portal vein thrombosis (PVT) and COVID-19.
View Article and Find Full Text PDFSimultaneous portal vein thrombosis and splenic vein thrombosis in a COVID-19 patient: A case report and review of literature.
World J Clin Cases
June 2024
Department of Gastroenterology and Hepatology, Brooklyn Campus of the Veterans Affairs New York Harbor Healthcare System, Brooklyn, NY 11209, United States.
Background: It is well-described that the coronavirus disease 2019 (COVID-19) infection is associated with an increased risk of thrombotic complications. While there have been many cases of pulmonary emboli and deep vein thrombosis in these patients, reports of COVID-19 associated portal vein thrombosis (PVT) have been uncommon. We present a unique case of concomitant PVT and splenic artery thrombosis in a COVID-19 patient.
View Article and Find Full Text PDFSplanchnic Vein Thrombosis: The State-of-the-Art on Anticoagulant Treatment.
Hamostaseologie
August 2024
Department of Pathology, Faculty of Medicine and Surgery, University of Malta, Msida, Malta.
Splanchnic vein thrombosis (SVT) is a rare type of venous thromboembolism occurring within the splanchnic venous system. Portal vein thrombosis is the most common presentation, while Budd-Chiari syndrome is the least common. Liver cirrhosis and abdominal solid cancer are the main local risk factors for SVT, whereas myeloproliferative neoplasms are the predominant systemic risk factors.
View Article and Find Full Text PDFClinical Features and Long-Term Outcomes of a Pan-Canadian Cohort of Adolescents and Young Adults with Myeloproliferative Neoplasms: A Canadian MPN Group Study.
Leukemia
March 2024
Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada.
Myeloproliferative neoplasms (MPNs) are a group of chronic hematologic malignancies that lead to morbidity and early mortality due to thrombotic complications and progression to acute leukemia. Clinical and mutational risk factors have been demonstrated to predict outcomes in patients with MPNs and are used commonly to guide therapeutic decisions, including allogenic stem cell transplant, in myelofibrosis. Adolescents and young adults (AYA, age ≤45 years) comprise less than 10% of all MPN patients and have unique clinical and therapeutic considerations.
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