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http://dx.doi.org/10.1097/00043764-199603000-00001DOI Listing

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Article Synopsis
  • Lung cancer is a major health issue in Australia and New Zealand, with 16,000 new cases annually, and variations in care and outcomes have been noted over the years without established benchmarks.
  • A study utilized a modified eDelphi consensus process to define clinical quality indicators relevant to lung and thoracic cancer care, involving clinicians, patient advocates, and researchers from across the region.
  • Ultimately, 27 clinical quality indicators were agreed upon, aiming to improve the quality of care, with plans for future implementation using real-world data across Australia.
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Introduction: Lung cancer is the leading cause of cancer mortality, comprising the largest national cancer disease burden in Australia and New Zealand. Regional reports identify substantial evidence-practice gaps, unwarranted variation from best practice, and variation in processes and outcomes of care between treating centres. The Australia and New Zealand Lung Cancer Registry (ANZLCR) will be developed as a Clinical Quality Registry to monitor the safety, quality and effectiveness of lung cancer care in Australia and New Zealand.

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From 2018 to 2020, the United States Environmental Protection Agency (EPA) performed a risk evaluation of chrysotile asbestos to evaluate the hazards of asbestos-containing products (e.g. encapsulated products), including brakes and gaskets, allegedly currently sold in the United States.

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Ovarian surface epithelium as a source of ovarian cancers: unwarranted speculation or evidence-based hypothesis?

Gynecol Oncol

July 2013

Department of Obstetrics and Gynecology, University of British Columbia, 4500 Oak Street, Vancouver, BC, Canada V6H 3N1.

Objectives: There has been increasing evidence that high grade serous ovarian carcinomas (HGSOCs), the most common and most lethal of all ovarian cancers, originate in oviductal fimbriae and metastasize to the ovary. The alternate hypothesis, that ovarian carcinomas may originate within the ovarian stroma in inclusion cysts lined by ovarian surface epithelium (OSE), has been criticized and often dismissed on the basis of the OSE's embryonic origin, mesothelial phenotype, tissue-specific markers, questionable ability to undergo metaplasia, and the lack of identifiable precursor lesions. This review analyzes these criticisms and summarizes evidence indicating that OSE as a source of ovarian cancers cannot be ruled out.

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