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Review of Challenges in Performing Real-World Evidence Studies for Nonprescription Products.
Pragmat Obs Res
January 2025
Global Medical Affairs, GSK Consumer Healthcare Singapore Pte. Ltd, Singapore.
In recent years, regulatory authorities have signaled a willingness to consider real-world evidence (RWE) data to support applications for new claims and indications for pharmaceuticals. Historically, RWE studies have been the domain of prescription drugs, driven by the fact that clinical data on patients are routinely captured in medical records, claims databases, registries, etc. However, RWE reports of nonprescription drugs and supplements are relatively sparse due to methodological gaps in this area.
View Article and Find Full Text PDFA brief report of the status of self-medication with over-the-counter drugs: a pilot cross-sectional survey.
BMC Res Notes
January 2025
Graduate School of Pharmaceutical Sciences, Osaka University, 1-6 Yamadaoka, Suita City, 565-0871, Osaka, Japan.
Objective: The extent of perceived knowledge and usage status regarding over-the-counter (OTC) drugs among Japanese citizens remains unclear. This study aims to assess OTC drug use through a pilot cross-sectional survey.
Results: Conducted on April 30, 2023, at the Graduate School of Pharmaceutical Sciences, Osaka University, the survey garnered 180 valid responses.
Removal of Antibiotics in Breeding Wastewater Tailwater Using Microalgae-Based Process.
Bull Environ Contam Toxicol
January 2025
Key Laboratory of Three Gorges Reservoir Region's Eco-Environment, Ministry of Education, Chongqing University, Chongqing, 400045, China.
Ciprofloxacin (CIP) and oxytetracycline (OTC) are commonly detected antibiotic species in breeding wastewater, and microalgae-based antibiotic treatment technology is an environmentally friendly and cost-effective method for its removal. This study evaluated the effects of CIP and OTC on Scenedesmus sp. in the breeding wastewater tailwater and the removal mechanisms of antibiotics.
View Article and Find Full Text PDF[Social Determinants of Combined Use of Alcohol and Non-prescription Drugs in Older Adults: A Population-based Study in Chile].
Rev Med Chil
November 2024
Núcleo de Humanidades y Ciencias Sociales, Universidad del Desarrollo, Santiago, Chile.
Unlabelled: Alcohol consumption by older adults has been called the "silent epidemic." An aging population and high levels of alcohol consumption increase the future challenge for epidemiology and public health. In addition, the misuse of prescription drugs is a growing public health problem associated with increased hospitalizations and health complications in older adults.
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