A patient developed priapism following a single intramuscular injection of chlorpromazine for hiccups. Conservative management was unsuccessful. During surgical intervention on the 15th hospital day, the corpora cavernosa of the turgid penis was irrigated and aspirated with heparinized saline using No14 gauge needles. The patient did well postoperatively. The physiology of the erection and the pathophysiology of priapism are discussed.
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http://dx.doi.org/10.1016/s0361-1124(77)80171-8 | DOI Listing |
Sci Rep
December 2024
Molecular Biology and Genetics Laboratory (LGBM), UFMS - Federal University of Mato Grosso do Sul, Três Lagoas, Brazil.
Sickle cell anemia (SCA) is a monogenic blood disease with complex and multifactorial pathophysiology. The endocannabinoid system (ECS) could be a candidate for modulating SCA complications, such as priapism, as it has demonstrated an essential role in hematopoiesis, platelet aggregation, and immune responses. We evaluated the association of ECS-related single nucleotide polymorphisms (SNP) (FAAH rs324420, MAGL rs604300, CNR1 rs7766029, and CNR2 rs35761398) with priapism in a Brazilian SCA cohort.
View Article and Find Full Text PDFBJU Int
December 2024
Department of Urology, Fox Chase Cancer Center, Philadelphia, PA, USA.
Int J Impot Res
December 2024
Associate Professor in the Division of Urology, Department of Surgery, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Ischaemic priapism is a urological emergency characterised by a prolonged, painful erection unrelated to sexual stimulation. While several aetiological factors contribute to this condition, the pharmacological causes have gained significant attention in recent years. This narrative review aims to comprehensively assess ischaemic priapism, specifically focusing on its pharmacological aetiology.
View Article and Find Full Text PDFCan Vet J
December 2024
Garden State Veterinary Specialists, 246 Industrial Way West, Eatontown, New Jersey 07724, USA.
Objective: To determine the complication rate of canine scrotal urethrostomy (SU) performed with poliglecaprone 25 and identify risk factors for complications.
Animals: We studied 67 dogs treated with SU.
Procedure: Medical records of dogs that underwent SU between 2011 and 2023 at Garden State Veterinary Specialists and its satellite hospitals were reviewed.
Cureus
October 2024
Pediatric Surgery, All India Institute of Medical Sciences, Raipur, Raipur, IND.
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