Three new sesquiterpene ortho-naphthoquinones, davidianones A, B and C, together with four known compounds, mansonones E, F, H and I, were isolated from the root bark of Ulmus davidiana. On the basis of spectral data including pulse field gradient two-dimensional NMR spectroscopy, the structures of new compounds were established as 3-hydroxymethyl-6,9-dimethylnaphtho(1,8-b,c)pyran-7,8-dione, 6-methoxycarbonyl-3,9-dimethylnaphtho(1,8-b,c)pyran-7,8-dione, 6-dimethoxymethyl-3,9-dimethylnaphtho(1.8-b,c)pyran-7,8-d ion e, respectively. Their antioxidative activities were evaluated by a thiobarbituric acid method using rat liver microsomes, with mansonone F showing the greatest activity.
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Phytomedicine
December 2024
School of Biological Science and Technology, University of Jinan, Jinan, 250022, China. Electronic address:
Background: Renal fibrosis is a major pathological feature of many chronic kidney diseases, and traditional Chinese medicines (TCM) have shown promising therapeutic potential for treating renal fibrosis. Although the extracts or fractions of Morus alba leaves and twigs have been reported to ameliorate renal fibrosis, the beneficial effects of M. alba root bark (commonly known as Sang-Bai-Pi), a well-known TCM, on this disorder have not been investigated.
View Article and Find Full Text PDFArch Razi Inst
June 2024
School of Life Science, Central University of Karnataka, kalaburagi-585367, Karnataka, India.
Nature is a valuable resource, supplying remedies for the treatment of all diseases. Plant kingdom stands for a plethora of natural compounds that are well known for their utilization in therapeutic applications. They may pave the way for the development of new mediators with appropriate efficacy in many pathological disorders in the future.
View Article and Find Full Text PDF<i>Ormocarpum trichocarpum</i> (Taub.) Engl. is a shrub or small tree harvested from the wild as a source of food, traditional medicines and wood.
View Article and Find Full Text PDFFront Chem
December 2024
Key Laboratory of TCM Clinical Pharmacy, Shenzhen Baoan Authentic TCM Therapy Hospital, Shenzhen, China.
Background: Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) influenced by multiple factors. Berberine, an isoquinoline alkaloid derived from the root and bark of Franch., has shown promise in managing UC, but its underlying mechanisms remain unclear.
View Article and Find Full Text PDFMicrob Ecol
December 2024
College of Chemistry and Chemical Engineering, Key Laboratory of Chemical Engineering and Technology of State Ethnic Affairs Commission, North Minzu University, Yinchuan, 750021, China.
Soil salinization poses a substantial threat to global food security, particularly under the influence of climate change, and is recognized as one of the most urgent challenges in land degradation. This study aims to elucidate the challenges associated with managing arid and semi-arid saline-alkali lands in China's Ningxia province and propose feasible solutions. To assess moss crust colonization, we measured changes in organic matter and chlorophyll levels.
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