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Detection of the Novel HLA-A*02:01:01:257 Allele by Pacific Biosciences HiFi Sequencing in a Chinese Individual.
HLA
January 2025
Department of Hematology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
HLA-A*02:01:01:257 differs from HLA-A*02:01:01:01 by a single nucleotide substitution in intron 7.
View Article and Find Full Text PDFIdentification of the Novel HLA-A*02:1098 Allele by Sanger Dideoxy Nucleotide Sequencing in a Chinese Individual.
HLA
January 2025
Department of Laboratory Medicine, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
The HLA-A*02:1098 allele differs from HLA-A*02:07:01:01 by a single non-synonymous nucleotide change in exon 3.
View Article and Find Full Text PDFThe Novel HLA Allele, HLA-A*02:889, Identified by Sequence-Based Typing in a Chinese Individual.
HLA
December 2024
Department of Transfusion Research, Wuhan Blood Center, Wuhan, China.
HLA-A*02:889 differs from HLA-A*02:01:01:01 by one nucleotide exchange at position 506(C>G) with an amino exchange.
View Article and Find Full Text PDFCharacterisation of the Novel HLA-A*02:1189 Allele by Sequencing-Based Typing.
HLA
November 2024
Histocompatibility and Immunogenetics Laboratory, Clermont-Ferrand University Hospital, Clermont-Ferrand, France.
Article Synopsis
- HLA-A2*02:1189 and HLA-A*02:01:01:01 are two different variants of a protein called HLA-A.
- The difference between them is due to a single nucleotide change in the genetic code.
- This change occurs specifically at codon 275, which is located in exon 5 of the gene.
Mediation effect of plasma metabolites on the relationship between immune cells and the risk of prostatitis: A study by bidirectional 2-sample and Bayesian-weighted Mendelian randomization.
Medicine (Baltimore)
October 2024
Department of Urology, Wuhu Hospital of Traditional Chinese Medicine, Wuhu, Anhui Province, China.
According to the findings of multiple observational studies, immune disorder was a risk factor for prostatitis. However, it remained unknown whether there was a direct causal relationship between immune cells and prostatitis or whether this relationship was mediated by plasma metabolites. Based on the pooled data of a genome-wide association study (GWAS), a genetic variant was used to predict the effects of 731 immunophenotypes on the risk of prostatitis and determine whether the effects were mediated by 1400 metabolites.
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