To reduce the radiation dose from spiral (helical) CT, a custom-made aluminium filter was installed in the X-ray tube and a reduction of effective tube current was attempted. A pronounced reduction of effective tube current, namely, 6 and 3 mA, was achieved with 26 and 37 mm thick aluminium filters, respectively. Visualization of normal lung structure was accomplished with both 6 and 3 mA settings. However, images of 3 mA failed to delineate mediastinal structures because of marked beam hardening resulting from the bone structure of the thoracic inlet. Six mA was considered the lowest dose setting of spiral (helical) CT of the thorax that could be used for lung cancer screening.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Grids designed for tomography: Stereovision transmission electron microscopy makes it easy to determine the winding handedness of helical nanocoils.
Micron
January 2025
Health and Medical Research Institute, Department of Life Science and Biotechnology, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central-6, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8566, Japan. Electronic address:
Determining the handedness of helical nanocoils using transmission electron microscopy (TEM) has traditionally been challenging due to the deep depth of field and transmission nature of TEM, complementary techniques are considered necessary and have been practiced such as low angle rotary shadowing, scanning electron microscopy (SEM), or atomic force microscopy (AFM). These methods require customized sample preparation, making direct comparison difficult. Inspired by the need to identify the helical winding direction from TEM images alone, we developed a specialized tomography grid to capture stereo-pair images, enabling stereopsis.
View Article and Find Full Text PDFChiral helical scaffolds: Unlocking their potential in biomolecular interactions and biomedical applications.
Biotechnol Adv
January 2025
Department of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacky University, Hnevotinska 3, 775 15 Olomouc, Czech Republic. Electronic address:
Article Synopsis
- Molecules with spiral geometry, like DNA and proteins, are common in nature and serve as a basis for exploring helicenes, which are carbon-rich structures with unique optical and chiral properties.
- Helicienes are gaining traction in biomedicine for their applications in cell imaging, drug delivery systems, protective coatings for implants, biosensors, and drug discovery due to their ability to interact with biomolecules.
- The review highlights recent advancements in helicene derivatives that improve luminescence and photochemical properties, emphasizing their significance in enhancing bio-imaging and diagnostics in biomedical technology.
Numerical simulation study on the influence of bend diameter rate on the flow characteristics of nature gas hydrate particles.
Sci Rep
December 2024
Jiangsu Key Laboratory of Oil-Gas Storage and Transportation Technology, Changzhou University, Changzhou, 213164, Jiangsu, China.
Bend pipe is a common part of long distance pipeline. There is very important to study the flow law of hydrate particles in the bend pipe, and pipeline design will be optimized. In addition, the efficiency and safety of pipeline gas transmission will be improved.
View Article and Find Full Text PDFResearch on the effectiveness of multi-view slice correction strategy based on deep learning in high pitch helical CT reconstruction.
J Xray Sci Technol
December 2024
Center of Ultra-Precision Optoelectronic Instrument Engineering, Harbin Institute of Technology, Harbin, China.
Background: Recent studies have explored layered correction strategies, employing a slice-by-slice approach to mitigate the prominent limited-view artifacts present in reconstructed images from high-pitch helical CT scans. However, challenges persist in determining the angles, quantity, and sequencing of slices.
Objective: This study aims to explore the optimal slicing method for high pitch helical scanning 3D reconstruction.
Development of a low-dose strategy for propagation-based imaging helical computed tomography (PBI-HCT): high image quality and reduced radiation dose.
Biomed Phys Eng Express
December 2024
Division of Biomedical Engineering, College of Engineering, University of Saskatchewan, Saskatoon, SK S7N 5A9, Canada.
Article Synopsis
- Propagation-based imaging computed tomography (PBI-CT) is gaining popularity for visualizing low-density materials thanks to its high resolution and image contrast, but it poses radiation risks in live animal imaging due to high doses.
- This study integrates a deep learning method called Sparse2Noise with PBI-CT to significantly reduce radiation exposure (up to 90%) while preserving image quality, showing improved results over traditional low-dose imaging methods.
- The findings indicate that Sparse2Noise provides a better signal-to-noise ratio compared to two other advanced low-dose algorithms, enhancing the effectiveness of PBI-CT for biomedical applications.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!