AI Article Synopsis

  • A study compared a synthetic derivative of prostaglandin E2 (PGE2) with 15-methyl prostaglandin F2 alpha (PGF2 alpha) for terminating midtrimester pregnancies (13-20 weeks) via intramuscular injection.
  • Both treatments had a high success rate of 97.5% for pregnancy termination.
  • However, the synthetic PGE2 derivative resulted in minimal or no side effects, while 15-methyl PGF2 alpha caused severe side effects like diarrhea and vomiting.

Article Abstract

A comparative study of a synthetic prostaglandin E2 (PGE2) derivative and 15-methyl prostaglandin F2 alpha (PGF2 alpha) in the termination of midtrimester pregnancy of 13-20 weeks of gestation by intramuscular route, showed 97.5% success rate in both the groups but in comparison to 15-methyl PGF2 alpha which produced severe side-effects eg. diarrhoea and vomiting, synthetic PGE2 derivative had minimal or no side-effects.

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