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Extensive Inactive Neurocysticercosis: A Case Report in Mbeya, Southern Highlands of Tanzania.
Int Med Case Rep J
January 2025
Kilimanjaro Christian Medical University College of Tumaini University, Moshi, Tanzania.
Background: Neurocysticercosis (NCC) and Acquired Human Immunodeficiency Syndrome (AIDS) are both highly prevalent in Africa. Clinical presentation of NCC ranges from asymptomatic to manifestations, including epileptic seizures, severe progressive headache, and focal neurological deficits. It is influenced by the number, size, location, and stage of the cysts, as well as the parasite's potential to cause inflammation and the immunological response of the host.
View Article and Find Full Text PDFA Comparative Study of ChatGPT and BingAI in Answering the National Eligibility Entrance Test for Postgraduates (NEET-PG)-Style Practice Questions: A Cross-Sectional Analysis.
Cureus
December 2024
Internal Medicine, Ross University School of Medicine, Saint Michael, BRB.
Purpose: The integration of artificial intelligence (AI) into medical education has witnessed significant progress, particularly in the domain of language models. This study focuses on assessing the performance of two notable language models, ChatGPT and BingAI Precise, in answering the National Eligibility Entrance Test for Postgraduates (NEET-PG)-style practice questions, simulating medical exam formats.
Methods: A cross-sectional study conducted in June 2023 involved assessing ChatGPT and BingAI Precise using three sets of NEET-PG practice exams, comprising 200 questions each.
Effects of Tocotrienol on Cardiovascular Risk Markers in Patients With Chronic Kidney Disease: A Randomized Controlled Trial.
J Nutr Metab
January 2025
Graduate Program in Medical Sciences, Fluminense Federal University (UFF), Niterói, Rio de Janeiro, Brazil.
Tocotrienols, isomers of vitamin E, may provide an effective nutritional strategy to mitigate common cardiovascular risks such as dyslipidemia, inflammation, and oxidative stress in patients with chronic kidney disease (CKD). This double-blind, placebo-controlled, randomized clinical trial aimed to evaluate the effects of a tocotrienol-rich fraction (TRF) supplementation (300 mg/day) on oxidative stress and inflammatory markers, including transcription factors in nondialysis (ND) and hemodialysis (HD) CKD patients for three months. Interleukin-6, tumor necrosis factor- (IL-6 and TNF-), C-reactive protein (CRP), lipid peroxidation, biochemical parameters, and transcription factors such as NRF2 and NF-B mRNA expression were evaluated.
View Article and Find Full Text PDFExploring the shared gene signatures and mechanism among three autoimmune diseases by bulk RNA sequencing integrated with single-cell RNA sequencing analysis.
Front Mol Biosci
January 2025
Department of Neurology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China.
Background: Emerging evidence underscores the comorbidity mechanisms among autoimmune diseases (AIDs), with innovative technologies such as single-cell RNA sequencing (scRNA-seq) significantly advancing the explorations in this field. This study aimed to investigate the shared genes among three AIDs-Multiple Sclerosis (MS), Systemic Lupus Erythematosus (SLE), and Rheumatoid Arthritis (RA) using bioinformatics databases, and to identify potential biomarkers for early diagnosis.
Methods: We retrieved transcriptomic data of MS, SLE, and RA patients from public databases.
Accelerating materials property prediction via a hybrid Transformer Graph framework that leverages four body interactions.
NPJ Comput Mater
January 2025
School of Mechanical, Aerospace, and Manufacturing Engineering, University of Connecticut, Storrs, CT USA.
Machine learning has advanced the rapid prediction of inorganic materials properties, yet data scarcity for specific properties and capturing thermodynamic stability remains challenging. We propose a framework utilizing a Graph Neural Network with composition-based and crystal structure-based architectures, combined with a transfer learning scheme. This approach accurately predicts energy-related properties (e.
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