Download full-text PDF |
Source |
---|
Int J Biochem Cell Biol
December 2024
Institute of Biology and Medicine, College of Life Science and Health, Wuhan University of Science and Technology, Wuhan, Hubei 430081, China. Electronic address:
Considering the high degree of malignancy, recurrence rate and poor prognosis, exploring promising targets is an imperious strategy for colorectal carcinoma therapy. Recent studies have indicated that GABPα plays a role in cancer aggressiveness, but its exact function and regulatory mechanisms in colorectal cancer progression remain unclear. This study aims to explore the biological role of GABPα and its upstream regulator, miR-378a-5p, in modulating cancer progression.
View Article and Find Full Text PDFSoc Stud Sci
December 2024
Center for the Humanities, Wesleyan University, Middletown, CT, USA.
What does a postcolonial inquiry into technoscience do? And what is it for? I develop these questions by reconsidering one powerful idea: that science and technology studies (STS) is postcolonial when it elucidates the hybridity, heterogeneity, and indeterminacy of global technoscientific formations, and does so to falsify colonial fantasies of hegemony expressed in imperious conceptual generalities and sovereign universalisms. Revisiting Warwick Anderson's expositions of postcolonial STS-initiated in this journal two decades ago-I reflect on the form and force of this critical operation. Despite an animating aversion to universalisms, the pursuit of hybridity and heterogeneity may ultimately universalize a liberal metaphysics of agency.
View Article and Find Full Text PDFJ Genet Eng Biotechnol
December 2024
ICAR-Vivekananda Parvatiya Krishi Anusandhan Sansthan, Almora 263601, UK, India.
Identification and characterization of crop mutants through molecular marker analysis are imperious to develop desirable traits in mutation breeding programs. In the present study, macromolecular variations with altered morphological, quantitative, and biochemical traits were generated through chemically induced mutagenesis via alkylating agents and heavy metals. Statistical analysis based on quantitative traits indicating enhanced mean value in mutant lines selected from the M generation as compared to previous generations.
View Article and Find Full Text PDFCurr Microbiol
October 2024
Department of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Acinetobacter baumannii and Acinetobacter nosocomialis are the imperious pathogens in the intensive care units. We aimed to explore the genomic features of these pathogens to understand the factors influencing their plasticity. Using next-generation sequencing, two carbapenem-resistant A.
View Article and Find Full Text PDFSci Total Environ
September 2024
Institut Pasteur de la Guadeloupe, Les Abymes, Guadeloupe, France. Electronic address:
Free-living amoebae (FLA) such as Acanthamoeba, Balamuthia mandrillaris, Naegleria fowleri and Sappinia pedata are naturally widespread in freshwater, causing rare but fatal and debilitating infections in humans. Although recent studies have shown an increase in infection rates, there is a paucity of epidemiological studies regarding the presence of these emerging pathogens in water. Herein, we studied the diversity and relative abundance of thermophilic FLA in different recreational baths in a tropical climate for 5 years.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!