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[Opioid prescriptions for insured individuals without cancer in Germany: data from the BARMER].
Schmerz
December 2024
PMV Forschungsgruppe an der Medizinischen Fakultät und Universitätsklinikum Köln, Universität zu Köln, Köln, Deutschland.
Background: The importance of opioids in the treatment of non-cancer pain is under debate. No current data are available from Germany on the prevalence of opioid treatment for non-cancer pain.
Aim Of The Study: Data on the prevalence of short- and long-term opioid prescriptions for patients without cancer, prescribed agents, co-medication, specialty of prescribing physicians, demographic and clinical characteristics of patients.
Relationships between the qNOX, qCON, burst suppression ratio, and muscle activity index of the CONOX monitor during total intravenous anesthesia: a pilot study.
J Clin Monit Comput
December 2024
Department of Anesthesiology and Intensive Care, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Article Synopsis
- The study investigates how different processed EEG indices, specifically qCON (hypnotic level) and qNOX (nociception), interact during propofol anesthesia in patients.
- It finds strong linear relationships among qCON, qNOX, EMG activity, and burst suppression, indicating that these indices can help differentiate the hypnotic and pain-relief aspects of anesthesia.
- A key conclusion is that high qCON levels depend on EMG activity, highlighting potential challenges in detecting wakefulness without EMG, and noting that high opioid doses may affect the relationship between qCON and qNOX.
Comparing Different Multimodal Analgesia Protocols for Primary Total Knee Arthroplasty-A Retrospective Cohort Analysis.
J Clin Med
July 2024
Medical Faculty Heidelberg, Department of Anesthesiology, Heidelberg University, Im Neuenheimer Feld 420, 69120 Heidelberg, Germany.
Several local regional anesthesia regimes have been described in the literature to reduce post-surgical pain following total knee arthroplasty (TKA), but it is unclear which regime has the best analgetic effect combined with the best motor function. The aim of this study was to determine if patients with infiltration between the popliteal artery and capsule of the posterior knee (IPACK) combined with an adductor canal block (SACB) had less pain, better motor function, and less opioid consumption after TKA than patients with a femoral nerve block (FNB) combined with a popliteal sciatic nerve block (PSB). In a retrospective cohort analysis, 342 patients following primary TKA were examined; 175 patients were treated with an IPACK combined with a SACB, and 167 patients with a femoral FNB combined with a PSB.
View Article and Find Full Text PDFDexmedetomidine as a total intravenous anesthetic in pediatric patients undergoing cleft lip and palate surgery: a case series.
J Med Case Rep
July 2024
Department of Plastic and Reconstructive Surgery, Rumah Sakit Umum Pusat Persahabatan, Jl. Persahabatan Raya No. 1, Jakarta Timur, 13230, Indonesia.
Background: Surgery for pediatric cleft lip and palate repair often utilizes high-dose opioids and inhaled anesthesia, thereby causing postoperative complications such as desaturation and/or severe agitation after anesthesia. These complications are detrimental to the child and medical personnel and cause tremendous psychologic stress to parents. Our aim is to decrease these complications through dexmedetomidine, an alpha-2 receptor agonist with anxiolytic, sympatholytic, and analgetic properties.
View Article and Find Full Text PDFThe analgetic effect of adjuvants in local infiltration analgesia - a systematic review with network meta-analysis of randomized trials.
J Clin Anesth
October 2024
Department of Anaesthesiology and Intensive Care Medicine, University Hospital Marburg, Philipps University of Marburg, Germany.
Background: Local infiltration analgesia is commonly used for postoperative pain control after several surgical procedures including intra- and peri-articular as well as wound infiltration. Even though, various adjuvants injected with the local anesthetic have been studied in pairwise comparison or compared to peripheral nerve blocks, the question which adjuvant or combination of adjuvants is the most effective in prolonging the duration of different types of local infiltration analgesia (LIA) has not been answered conclusively.
Objective: The objective of this network meta-analysis was to determine the analgesic effectiveness and safety of adjuvants in local infiltration analgesia.
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