Art glassware and sinonasal cancer: report of three cases.

Am J Ind Med

Division of Workers' Preventive Medicine, University of Siena, Italy.

Published: July 1996

In a multicenter study on the occupational etiology of sinonasal cancer (s.n.c.) carried out in Italy, we collected information about three cases which had arisen among glass workers: an adenocarcinoma, a melanoma, and a squamocellular carcinoma. The three men worked many years as mixers and/or batchers in artistic glass factories in Tuscany (Italy). We propose a possible etiological role of arsenic dust.

Download full-text PDF

Source
http://dx.doi.org/10.1002/(SICI)1097-0274(199607)30:1<31::AID-AJIM5>3.0.CO;2-VDOI Listing

Publication Analysis

Top Keywords

sinonasal cancer
8
three cases
8
art glassware
4
glassware sinonasal
4
cancer report
4
report three
4
cases multicenter
4
multicenter study
4
study occupational
4
occupational etiology
4

Similar Publications

Objective: Our study aimed to update demographic profiles of sinonasal adenocarcinoma (SNAC) between 2000 and 2020, identify independent prognostic risk factors, and devise a predictive nomogram for overall survival (OS).

Methods: Utilizing the Surveillance, Epidemiology, and End Results (SEER) database, cases of SNAC from 2000 to 2020 were analyzed for incidence trends. Univariate and multivariate Cox regression models helped pinpoint factors impacting patient survival.

View Article and Find Full Text PDF

Impact of posterior septectomy on olfaction in endoscopic endonasal transsphenoidal surgery.

PLoS One

January 2025

Department of Otolaryngology-Head and Neck Surgery, Seoul Saint Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Background: Endoscopic endonasal transsphenoidal surgery is widely used to resect pituitary adenomas, yet its impact on olfactory function after resection of the posterosuperior nasal septum remains a concern. To optimize surgical techniques to preserve olfactory function, it is essential to understand the relationship between the extent of septal resection and olfactory outcomes.

Methods: This retrospective study analyzed 295 patients who underwent pituitary adenoma surgery.

View Article and Find Full Text PDF
Article Synopsis
  • Sinonasal inverted papilloma (SNIP) has a high recurrence rate and the potential to become malignant, but its specific metabolic pathways and biomarkers are not fully understood.
  • RNA sequencing identified significant gene alterations related to the estrogen biosynthesis pathway and highlighted five key biomarkers (AKR1B10, CYP1B1, CYP2C19, CYP3A5, and HSD17B13) that were correlated with SNIP pathogenesis.
  • Functional analysis indicated that these biomarkers are involved in epithelial cell proliferation and EGFR signaling regulation, suggesting their potential as diagnostic and therapeutic targets for managing SNIP.
View Article and Find Full Text PDF

Fibro-osseous lesions of the sinonasal tract: a contemporary review.

Curr Opin Otolaryngol Head Neck Surg

February 2025

Department of Otolaryngology - Head & Neck Surgery, University of Florida, Gainesville, Florida, USA.

Purpose Of Review: Fibro-osseous lesions (FOL) are benign, slow-growing lesions that are often incidentally discovered in the sinonasal cavity. They may necessitate surgical resection in patients with postobstructive sinusitis, or in cases of cranial nerve and orbital compression. We examine the recent advancements in otolaryngology relating to diagnostic characteristics and treatments for FOL, with emphasis on new technologies to improve outcomes and reduce recurrence.

View Article and Find Full Text PDF

DEK::AFF2 fusion nonkeratinizing squamous cell carcinoma (NKSCC) is an emerging entity in the sinonasal tract, temporal bone, and skull base. However, the clinical behavior of these tumors has not been well studied. Here, we report the largest cohort of DEK::AFF2 carcinomas to determine if morphology, mitotic rate, and/or Ki-67 IHC are associated with patient outcomes, including a comparison with high-risk human papillomavirus (HPV)-associated and independent patients.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!