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Host Preferences and Impact of Climate on Blood Feeding in Group from South Africa.

Trop Med Infect Dis

October 2024

Wits Research Institute for Malaria, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg 2193, South Africa.

and (members of the group) are generally not considered malaria vectors. However, both species were recently identified as potential vectors in South Africa. A critical factor needed to determine their role in malaria transmission is their preference for human blood.

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Article Synopsis
  • Lymphatic filariasis (LF) is a neglected tropical disease caused by mosquito-borne parasites affecting 51 million people globally, with mass drug administration recommended by WHO in endemic areas like coastal Kenya.
  • In 2022, a study collected over 18,000 mosquitoes from LF-endemic counties in Kenya to analyze infection rates of Wuchereria bancrofti, utilizing molecular xenomonitoring methods.
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Background: Protein analysis using matrix-assisted laser desorption/ionisation time-of-flight mass-spectrometry (MALDI-TOF MS) represents a promising tool for entomological surveillance. In this study we tested the discriminative power of this tool for measuring species and blood meal source of main Afrotropical malaria vectors on the Kenyan coast.

Methods: Mosquito collections were conducted along the coastal region of Kenya.

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Mosquitoes are arthropods that represent a real public health problem in Africa. Morphology and molecular biology techniques are usually used to identify different mosquito species. In recent years, an innovative tool, matrix-assisted desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), has been used to identify many arthropods quickly and at low cost, where equipment is available.

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