SOD activity and -SH compounds in the liver and RBCs, and some hematological parameters were investigated in control rats and in those submitted to chronic (3 months) intoxication with ethanol. We found significantly lower SOD activity and a decrease in -SH groups in the liver and RBCs of ethanol-treated rats in comparison with the control group. The hemoglobin content and mean corpuscular hemoglobin concentration were reduced, while mean corpuscular volume of RBCs was increased when compared with the control group.
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Metab Brain Dis
January 2025
Key Laboratory of Longevity and Aging-Related Disease of Chinese Ministry of Education, Center for Translational Medicine, School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi, China.
2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione (DMDD) is a cyclohexanedione compound extracted from the roots of Averrhoa carambola L. Several studies have documented its beneficial effects on diabetes, Alzheimer's disease, and cancer. However, its potential neuroprotective effects on Parkinson's disease (PD) have not yet been explored.
View Article and Find Full Text PDFNutrients
January 2025
Orthodontics, Department of Conservative Odontology, Faculty of Dental Medicine, "Iuliu Hațieganu" University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Unlabelled: Honey is abundant in bioactive compounds, which demonstrate considerable therapeutic effects, particularly on oxidative stress and inflammation.
Objectives: This work sought to evaluate the antioxidant mechanisms of Manuka honey (MH) and Ohia Lehua honey (OLH), correlating them with phytochemical analyses in a rat model of experimentally induced inflammation.
Methods: The identification of polyphenolic compounds in the extracts was carried out using HPLC-ESI MS.
Pharmaceuticals (Basel)
December 2024
Department of Bionano Technology, Gachon Bionano Research Institute, Gachon University, 1342 Seongnam-daero, Sujeong-gu, Seongnam-si 461-701, Gyeonggi-do, Republic of Korea.
Background: (Cardamom) and (Fennel) are well-known spices and are also used as natural mouth fresheners. This study was performed to evaluate their neuroprotective ability based on certain acellular and cellular assays.
Methods: Hexane and ethyl acetate extracts were prepared using cardamom and fennel seeds.
Antioxidants (Basel)
January 2025
Department for Innovation in Biological, Agro-Food and Forest Systems, Tuscia University, 01100 Viterbo, Italy.
In addition to the immature edible flower heads, the cultivation of globe artichoke ( L. var. (L.
View Article and Find Full Text PDFTalanta
January 2025
School of Life Sciences, Faculty of Science, The University of Technology Sydney, Sydney, NSW, Australia.
Metabolomics analyses enable the examination and identification of endogenous biochemical reaction products, revealing information on the metabolic pathways and processes active within a living cell or organism. Determination of metabolic shifts can provide important information on a treatment or disease. Unlike other omics fields that typically have analytes of the same chemical class with common building blocks, those that fall under the nomenclature of metabolites encompass a wide array of different compounds with very diverse physiochemical properties.
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