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Nocardiosis in systemic lupus erythematosus patients treated with rituximab: Report of two cases and systematic review of literature.
Lupus
February 2025
Unidad de Enfermedades Autoinmunes Sistémicas, Hospital Universitario Clínico San Cecilio, Granada, España.
Background: The relationship between systemic lupus erythematosus (SLE) patients treated with rituximab and nocardiosis remains unclear.
Cases Report: A 55-year-old female with lupus nephritis II and smoking history, was treated with high-dose steroids, immunoglobulins, rituximab, and azathioprine. She developed infectious loci in the lungs, hip, and brain.
Multiple autoimmunity: neuromyelitis optica spectrum disorder with Lambert-Eaton myasthenic syndrome.
Pract Neurol
February 2025
Department of Neurology, Royal London Hospital, Barts Health NHS Trust, London, UK
A 56-year-old woman with a background of neuromyelitis optica spectrum disorder associated with aquaporin-4 antibodies (AQ4-NMOSD) treated with azathioprine, presented with a 2-month history of declining mobility, weight loss and hoarse voice. She had a history of autoimmune thyrotoxicosis and treated hypertension. Given her smoking history, the initial clinical concern was of malignancy.
View Article and Find Full Text PDFAssociation between non-melanoma skin cancer, psoriasis, and immunomodulatory therapy: a national epidemiologic study.
Arch Dermatol Res
December 2024
Department of Dermatology, Baylor College of Medicine, Houston, TX, USA.
The association between psoriasis and non-melanoma skin cancer (NMSC) remains inconsistent despite biologic plausibility. Immunosuppressive effects of systemic psoriasis treatments have also been hypothesized to contribute to the development of NMSC as well. However, data assessing the risk of NMSC associated with immunomodulatory psoriasis medications, particularly newer biologic therapies, are limited.
View Article and Find Full Text PDFMalignancies After Heart Transplantation.
Transpl Int
September 2024
Transplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden.
Heart transplant patients have an increased risk of developing cancer. Patients who underwent HTx between 1985 and 2017 were included. Detection of cancer was obtained by cross-checking the study population with the Swedish Cancer-Registry and the Cause-of-Death-Registry.
View Article and Find Full Text PDFPrevalence of Apical Periodontitis in Patients with Autoimmune Liver Diseases on Immune Suppressants and Immune Modulators: A Cross-sectional Study.
J Endod
June 2024
Department of Conservative Dentistry and Endodontics, University of Cagliari, Cagliari, Italy.
Introduction: Autoimmune liver diseases (ALDs) are chronic conditions generated by an immune-mediated autoaggressive inflammatory reaction in genetically susceptible individuals. The purpose of this study was to evaluate the prevalence of apical periodontitis (AP) in patients suffering from ALDs undergoing treatment with the immune suppressants glucocorticoids, azathioprine, and/or ursodeoxycholic acid.
Methods: The ALD group included 46 patients (11 men and 35 women, average age = 57.
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