[Benign sacro-coccygeal teratoma. A case report in Yaounde, Cameroon].

Med Trop (Mars)

Service de Radiologie, l'Hôpital Militaire de Yaoundé, Cameroun.

Published: October 1996

The authors describe a cases of sacrococcygeal teratoma observed in an infant after pregnancy without ultrasound surveillance. The mass was located in the buttock with a mainly exo-pelvic extension. There was no other malformation. Ultrasound examination revealed a heterogeneous structure with solid and liquid areas. Alphafoetoprotein level was high but the beta-HCG level was normal. The surgical specimen weighed 1990 grams and presented microcystic cavities and calcifications. Histological examination confirmed the diagnosis of benign complex multitissue teratoma. Postoperative recovery was uneventful and development of the child was normal 45 months after the procedure. The authors review the histologic, diagnostic, and prognostic features of teratomas and emphasize the importance of early surgical management, which is usually feasible in Africa.

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  • The condition is linked to mutations in the MNX1 gene on chromosome 7q36, with the majority of familial cases showing heterozygous loss-of-function mutations, while about 30% of sporadic cases do.
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