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Mental Health Care Utilization and Prescription Rates Among Children, Adolescents, and Young Adults in France.
JAMA Netw Open
January 2025
CEReSS, Research Centre on Health Services and Quality of Life, Aix Marseille University, Marseille, France.
Importance: Amid escalating mental health challenges among young individuals, intensified by the COVID-19 pandemic, analyzing postpandemic trends is critical.
Objective: To examine mental health care utilization and prescription rates for children, adolescents, and young adults before and after the COVID-19 pandemic.
Design, Setting, And Participants: This population-based time trend study used an interrupted time series analysis to examine mental health care and prescription patterns among the French population 25 years and younger.
Chronic olanzapine treatment leads to increased opioid receptor expression and changes in feeding regulating neurons in the female rat hypothalamus.
Psychoneuroendocrinology
January 2025
Core Centre for Molecular Morphology, Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Pathology, Aarhus University Hospital, Aarhus, Denmark.
Article Synopsis
- * The study involved female rats treated with olanzapine, revealing immediate increases in eating (hyperphagia) and continued weight gain, alongside specific changes in opioid receptor expression in the hypothalamus.
- * Findings suggest that chronic olanzapine leads to increased expression of certain opioid receptors in areas of the hypothalamus linked to appetite regulation, supporting the use of opioid receptor antagonists to counteract olanzapine's negative metabolic effects.
Pharmacological Treatment of Binge Eating Disorder and Frequent Comorbid Diseases.
CNS Drugs
September 2024
Lindner Center of HOPE, Mason, OH, USA.
Binge eating disorder (BED) is the most common specific eating disorder (ED). It is frequently associated with attention deficit hyperactivity disorder (ADHD), depression, bipolar disorder (BD), anxiety disorders, alcohol and nicotine use disorder, and obesity. The aim of this narrative review was to summarize the evidence for the pharmacological treatment of BED and its comorbid disorders.
View Article and Find Full Text PDFPsychotropic drugs, eating behaviour and weight gain.
Curr Opin Psychiatry
September 2024
Mental Health service, Fiona Stanley Fremantle Hospitals Group, Murdoch, WA, Australia.
Purpose Of Review: Psychotropic drug related weight gain is a common side-effect of significant concern to both clinicians and patients. Recent studies and treatment guidelines strongly support taking preventive and early treatment approaches to psychotropic drug-related weight gain (PDWG). Arguably the main pathway that PDWG occurs is via changes in eating behaviour leading to increased caloric intake.
View Article and Find Full Text PDFComparative physiological effects of antipsychotic drugs in children and young people: a network meta-analysis.
Lancet Child Adolesc Health
July 2024
Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK; Psychiatric Imaging Group, Medical Research Council London Institute of Medical Sciences, Imperial College London, London, UK.
Background: The degree of physiological responses to individual antipsychotic drugs is unclear in children and adolescents. With network meta-analysis, we aimed to investigate the effects of various antipsychotic medications on physiological variables in children and adolescents with neuropsychiatric and neurodevelopmental conditions.
Methods: For this network meta-analysis, we searched Medline, EMBASE, PsycINFO, Web of Science, and Scopus from database inception until Dec 22, 2023, and included randomised controlled trials comparing antipsychotics with placebo in children or adolescents younger than 18 years with any neuropsychiatric and neurodevelopmental condition.
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