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Hemorrhagic cholecystitis afflicted with glanzmann thrombasthenia patient.
J Family Med Prim Care
November 2024
Department of Basic Science College of Medicine, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Article Synopsis
- Hemorrhagic cholecystitis is a rare but serious condition that can occur if the gallbladder bursts, necessitating urgent medical intervention.
- A 27-year-old man with Glanzmann's thrombasthenia visited the emergency department multiple times, initially presenting with ear and later chest pain, before being misdiagnosed and sent home.
- Upon returning with abdominal symptoms, an ultrasound confirmed cholecystitis, leading to an emergency surgery that uncovered the hemorrhagic cholecystitis diagnosis.
Ultrahypofractionated Versus Normofractionated Preoperative Radiotherapy for Soft Tissue Sarcoma: A Multicenter, Prospective Real-World-Time Phase 2 Clinical Trial.
Cancers (Basel)
December 2024
Sarcoma Service, Department of Orthopedics and Trauma, Sarcoma Center, Radiation Oncology, LUKS University Hospital, 6000 Luzern, Switzerland.
The historically most commonly used preoperative radiotherapy regimen for soft tissue sarcomas (STSs) consists of 50 Gray (Gy) delivered in 25 fractions over 5 weeks, achieving excellent local control, but with significant challenges due to prolonged treatment duration and early side effects. Reducing therapy duration while maintaining optimal local and distant control would be highly beneficial for patients. We aimed to investigate the outcome of an ultrahypofractionated radiotherapy (uhRT) regimen which may represent a shorter and more patient-friendly alternative.
View Article and Find Full Text PDFBackground: Glanzmann thrombasthenia (GT) is a rare disease with an autosomal recessive inheritance pattern. This disorder is not so uncommonly encountered in routine clinical practice and laboratory settings in Pakistan let alone in the rest of the world. To describe the bleeding phenotype of GT and treatment outcomes in over one hundred patients in north Pakistan.
View Article and Find Full Text PDFOral invasive procedures in Glanzmann thrombasthenia: a retrospective observational study.
Res Pract Thromb Haemost
November 2024
University of Strasbourg, Faculty of Dental Surgery, Strasbourg, France.
Background: Glanzmann thrombasthenia (GT) is a very rare autosomal inherited bleeding disease affecting megakaryocyte lineage with impacts on oral health such as gingival bleeding, which requires specific management protocols. Very few clinical cases have been published in the dental and hematologic literature.
Objectives: This study focuses on a series of 21 patients affected specifically by GT and their hemorrhagic prophylaxis management with the use of recombinant activated factor VII (rFVIIa) for dental extractions and full-mouth debridement.
Understanding preoperative health-related quality of life in rotator cuff tear patients: role of patients' characteristics.
BMC Musculoskelet Disord
December 2024
Schulthess Klinik, Research and Development Department - Shoulder and Elbow Surgery, Zurich, Switzerland.
Background: Assessing health-related quality of life (HRQoL) is a widely employed method in orthopedics to evaluate patient well-being and measure the effectiveness of surgical interventions. Understanding the relationship between specific baseline factors and preoperative HRQoL can help clinicians identify patients at risk for low quality of life and thus, develop preventive strategies that adequately address individual patient needs. The objective was to assess associations between baseline factors and preoperative HRQoL in patients undergoing arthroscopic rotator cuff repair (ARCR).
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