As indicated by blood tests, chronic glomerulonephritis (CGN) patients with intact renal function have impaired lipid peroxidation and antioxidant defense. In nephrotic syndrome these plasm changes are more pronounced, but red cells remain relatively intact. Persistent nephrotic syndrome produces a trend to shifts in red blood picture. In CGN patients free of nephrotic syndrome red cells exhibited lipid peroxidation and weak antioxidant defense. The above facts support the validity of antioxidants use in combined treatment of CGN.
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