In this paper we report on the longitudinal stability of IQ in 26 children with unilateral left (LL N = 18) or right (RL N = 8) hemisphere damage. Results revealed (i) normal or near normal levels of intellectual performance in both LL and RL groups, and, (ii) hemispheric differences in the level and stability of intellectual performance. RL children achieved lower IQ scores than LL children and were more likely to decrease in VIQ over time. Cross-sectional analyses revealed a tendency for injury sustained earlier (e.g. during the first 5 years of age), rather than later in development to be associated with lower IQ scores.
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http://dx.doi.org/10.1016/0028-3932(94)90071-x | DOI Listing |
World J Emerg Surg
January 2025
Department of General and Emergency Surgery, Anesthesia and Intensive Care Unit, Maurizio Bufalini Hospital, Cesena, Italy.
Spine Deform
January 2025
Department of Orthopedic Surgery, Children's Mercy Kansas City, Kansas City, Missouri, USA.
Purpose: Scoliosis is a complex multi-dimensional deformity of the spine that is common in children and adults. Of the various treatments for scoliosis, one is posterior spinal fusion with instrumentation. The rods typically used are composed of titanium or cobalt-chrome.
View Article and Find Full Text PDFArch Dis Child
January 2025
Northern Jiangsu People's Hospital, Yangzhou, Jiangsu, People's Republic of China.
Background: The prevalence of inflammatory bowel disease (IBD) among Chinese adolescents has continued to increase in recent years. Adolescents with IBD interrupted their schooling due to the diagnosis and treatment of the disease. And when the condition stabilises, they will return to school.
View Article and Find Full Text PDFJ Vis Exp
January 2025
Institute of Biochemistry and Molecular Biology, Hengyang Medical School, University of South China; National Health Commission Key Laboratory of Birth Defect Research and Preventio, Hunan Provincial Maternal and Child Health Care Hospital;
Both DNA replication and RNA transcription utilize genomic DNA as their template, necessitating spatial and temporal separation of these processes. Conflicts between the replication and transcription machinery, termed transcription-replication conflicts (TRCs), pose a considerable risk to genome stability, a critical factor in cancer development. While several factors regulating these collisions have been identified, pinpointing primary causes remains difficult due to limited tools for direct visualization and clear interpretation.
View Article and Find Full Text PDFJ Cancer Res Clin Oncol
January 2025
Key Laboratory of Laboratory Medicine, Ministry of Education of China, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, 325035, Zhejiang, China.
Purpose: Growing evidence suggests that the tyrosine phosphatase SHP2 is pivotal for tumor progression. Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer, characterized by its high recurrence rate, aggressive metastasis, and resistance to chemotherapy. Understanding the mechanisms of tumorigenesis and the underlying molecular pathways in TNBC could aid in identifying new therapeutic targets.
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