A case with chondrosarcoma of rib, which is relatively uncommon in Japan, in a 61-year-old man is reported. Chest X-ray examination revealed an abnormal shadow in the right of the chest wall. Chest CT scan and MRI disclosed the tumor to have been arosen from the right 5th rib protruding into the thoracic cavity. Surgical resections of the tumor with parts of the 4th and 5th ribs and parietal pleura were performed. The defect of the chest wall was repaired with muscle. The tumor measured 3.0 x 3.0 x 3.5 cm in size and was a chondrosarcoma of the low grade malignancy, histologically. Post operative course was uneventful with no adjuvant therapy.
Download full-text PDF |
Source |
---|
Front Oncol
January 2025
Department of Thoracic Surgery, Lanzhou University Second Hospital, Lanzhou, Gansu, China.
Chondrosarcoma-like malignant giant cell tumor (GCT) of the rib is an extremely rare and aggressive tumor, particularly in adolescents. This case report describes a 19-year-old female presenting with a GCT of the rib with chondrosarcomatous differentiation, highlighting the challenges posed by its unusual location and pathological complexity. Multidisciplinary diagnostic approaches, including advanced imaging, immunohistochemistry (IHC), and pathology, were essential for confirming the diagnosis.
View Article and Find Full Text PDFRadiol Case Rep
March 2025
Centre for Innovative Drug Development and Therapeutic Trials for Africa (CDT-Africa), College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Laryngeal chondroma is a very rare laryngeal tumor that commonly presents as dysphonia and dyspnea. A combination of clinical, histological, and radiological data has paramount importance for accurate diagnosis of this rare disease. It is difficult to differentiate laryngeal chondroma from chondrosarcoma solely based on radiological imaging; therefore, radiologists need to specify the origin of the tumor and the level of extension.
View Article and Find Full Text PDFJ Int Med Res
January 2025
Department of Orbital Disease and Ocular Plastic Surgery, The Second Hospital of Jilin University, No. 4026 Yatai Street, Changchun, Jilin Province, China.
Extraskeletal orbital mesenchymal chondrosarcoma is an extremely rare and highly aggressive tumor. We herein report a case involving a woman in her early 20s diagnosed with orbital mesenchymal chondrosarcoma. This case report aims to increase recognition and understanding of this condition.
View Article and Find Full Text PDFInt J Surg Case Rep
January 2025
Faculty of Medicine, University of Damascus, Damascus, Syrian Arab Republic.
Introduction: Mesenchymal chondrosarcoma (MC) is a high-grade variant of chondrosarcoma, essentially composed of poorly differentiated spindle cells interspersed with areas of cartilage or chondroid matrix. MC is extremely rare; it only accounts for 0.1 % of head and neck tumors and for only 1 % of all chondrosarcomas (CSs).
View Article and Find Full Text PDFHum Pathol
January 2025
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, 30322, USA. Electronic address:
Introduction: Extraskeletal myxoid chondrosarcoma (EMC) is a rare sarcoma defined by NR4A3 gene rearrangements, typically featuring uniform cells with eosinophilic cytoplasm and mild atypia, arranged in cords or clusters within a chondromyxoid stroma. A cellular variant, characterized by increased cellular density and a solid growth pattern, has been recognized.
Methods: We encountered three cases of round cell sarcomas, diagnosed as EMC based on NR4A3 or NR4A2 rearrangements.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!