Purpose: The aim of this study was to evaluate the CT findings of amebic liver abscesses and its usefulness for treatment.
Methods: CT was performed in 51 patients with proved amebic liver abscess. CT studies were made before and after contrast injection.
Results: Among the 98 abscesses, 66% occurred in the right lobe. 66% of the patients presented a solitary abscess. The diameters were found between 2 cms to 15 cms. The mean was 7 cms. An enhancing wall was present in 84%; the margins were festooned in 75%, smooth in the other cases; internal septations were noted in 57%. High density material within the abscess, before injection of contrast was seen in 50%. 30% of patients had focal intra-hepatic biliary dilatation, 27% right pleural effusion, 23% peri-hepatic fluid collection. One hepatic-colic fistula and one hepato-pulmonary fistula were not suspected on U.S. examination. Percutaneous aspiration was done in 31% of the patients, when the diameter of the abscesses were more than 10 cms or when they were seen in the left lobe or when fever or pain did not disappear after treatment.
Conclusion: CT scan may be helpful in diagnosis of amebic liver abscess at an early stage or later when a complication is suspected. CT scan can also help to indicate and safely perform a percutaneous therapeutic aspiration.
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Diagn Microbiol Infect Dis
January 2025
Division of Infectious Diseases, Naval Medical Center San Diego, 34800 Bob Wilson Drive, San Diego, CA, 92134, USA; Department of Medicine, Uniformed Services University, 4301 Jones Bridge Road, Bethesda, MD 20814, USA.
Entamoeba histolytica infections range from asymptomatic intestinal amebiasis to more severe syndromes like invasive colitis or hepatic abscess. While diagnostic tests available for assessing these infections have evolved, the optimal use of newer diagnostics like enteric multiplex Polymerase Chain Reaction (PCR) panels has not been fully established. Here we describe the case of a 34-year-old male with an amebic liver abscess (ALA) that was diagnosed via multiplex Gastrointestinal (GI) PCR panel on formed stool and subsequently confirmed by testing liver abscess fluid (off-label) on the same multiplex GI PCR panel leading to rapid diagnosis and targeted treatment modification with excellent outcome.
View Article and Find Full Text PDFCureus
December 2024
Department of Anatomy, Ganesh Shankar Vidyarthi Memorial Medical College, Kanpur, IND.
Purpose Hepatic abscesses remain a significant clinical challenge due to high morbidity and mortality. This research aims to examine the etiological spectrum, management approaches, clinical features, and results in hepatic abscesses in a tertiary care facility in northern India, emphasizing the distinctions among pyogenic liver abscesses (PLAs) and amoebic liver abscesses (ALAs). Methods This retrospective study was done at GSVM Medical College, Kanpur, analyzing 725 patients with hepatic abscesses over a 10-year period.
View Article and Find Full Text PDFWorld J Hepatol
December 2024
Department of Surgery, University of Witwatersrand, School of Clinical Medicine, Johannesburg 2193, Gauteng, South Africa.
Background: Hepatic abscesses represent infections of the liver parenchyma from bacteria, fungi, and parasitic organisms. Trends in both abscess microbiology and management of abscesses (infective collections) have changed over the past decade. There is a paucity of published data regarding the clinicopathological features of liver abscesses in sub-Saharan Africa and other low-income and middle-income countries.
View Article and Find Full Text PDFFront Cell Infect Microbiol
January 2025
Department of Biomedical Science and Technology, School of Biological Sciences, Ramakrishna Mission Vivekananda Educational and Research Institute (RKMVERI), Kolkata, India.
Amoebae, fascinatingly diverse protists, showcase a dual nature that positions them as both friends and foes in our world. These organisms, defined by their distinctive pseudopodia, span a spectrum from harmful to helpful. On the darker side, species like pose serious health risks, causing intestinal and liver diseases, while the infamous "brain-eating" leads to fatal primary amoebic meningoencephalitis (PAM), with a daunting 97% mortality rate.
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