U.S. Naval Medical Research Unit 2, Jakarta, Indonesia.
Published: April 1996
AI Article Synopsis
Article Abstract
Strong positive CAMP reactions were demonstrated by 121 Vibrio cholerae O139 and 504 El Tor isolates, and weak positive CAMP reactions were shown by 235 non-O1, non O139 isolates when these isolates were tested by a modified CAMP technique. Thirty-five classical biotype V. cholerae O1 isolates included in the tests were all CAMP negative.
Background: Diarrhea caused by non-O1/O139-group e (NOVC) tends to be mild and can be readily overlooked. In this report, a NOVC strain designated XXM was isolated from the blood of a 68-year-old male undergoing surgical treatment for a bile duct malignancy in October 2023.
Methods: XXM was identified through a matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS).
Unlabelled: Bacteria have evolved diverse strategies to ensure survival under nutrient-limited conditions, where rapid energy generation is not achievable. Here, we performed a transposon insertion site sequencing loss-of-function screen to identify genes that promote pathogen fitness in stationary phase. We discovered that the aintenance of ipid symmetry (Mla) pathway, which is crucial for transferring phospholipids from the outer to the inner membrane, is critical for stationary phase fitness.
Non-O1/non-O139 Vibrio cholerae (NOVC) strains are a distinct group of Vibrio cholerae that do not cause epidemic cholera. NOVC infections usually cause mild forms of gastroenteritis, and rarely severe (extra)intestinal infections, mostly affecting immunocompromised patients. Here, we describe the clinical course of a patient with NOVC bacteremia causing multiple liver abscesses, after drinking from a freshwater well in a non-coastal area.
Shanghai-MOST Key Laboratory of Health and Disease Genomics, Shanghai Institute for Biomedical and Pharmaceutical Technologies (SIBPT), Fudan University, Shanghai, China.
The gene , encoding the mannitol transporter subunit IICBA of the phosphotransferase system, was the core gene with the greatest variability in and could be used as a new typing marker in . To expand its application, we performed an evolutionary analysis and found that the gene was present in nine phyla, 371 genera, and 1,662 species of bacteria. It is commonly found in pathogenic species of , followed by , , etc.
Objectives: On October 4, 2021, a cholera outbreak was reported in Kapilvastu District, one of Nepal's 26 districts bordering India. This study examined the outbreak's characteristics, response efforts, and the challenges faced.
Methods: A descriptive cross-sectional design was applied for the outbreak investigation.
