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Development of Chondroblastic Variant of Osteosarcoma After Root Channel Treatment in the Base of Maxillary Sinus.
Klin Padiatr
December 2024
Radiology, Bezmialem Vakif University, Istanbul, Turkey.
Magnetic Resonance Imaging Texture Analysis Based on Intraosseous and Extraosseous Lesions to Predict Prognosis in Patients with Osteosarcoma.
Diagnostics (Basel)
November 2024
Department of Diagnostic Radiology, School of Medicine, Tohoku University Graduate, Sendai 980-8574, Japan.
To construct an optimal magnetic resonance imaging (MRI) texture model to evaluate histological patterns and predict prognosis in patients with osteosarcoma (OS). Thirty-four patients underwent pretreatment MRI and were diagnosed as having OS by surgical resection or biopsy between September 2008 and June 2018. Histological patterns and 3-year survival were recorded.
View Article and Find Full Text PDFIntegrated single-cell analysis reveals heterogeneity and therapeutic insights in osteosarcoma.
Discov Oncol
November 2024
Department of Orthopaedics, Hangzhou Ninth People's Hospital, Hangzhou, China.
Osteosarcoma (OSA) is a primary bone malignancy characterized by its aggressive nature and high propensity for metastasis. Despite advancements in multimodal therapies, the clinical outcomes for OSA patients remain suboptimal, necessitating deeper molecular insights for improved therapeutic strategies. Here, we employed single-cell RNA sequencing (scRNA-seq) to elucidate the cellular heterogeneity and transcriptional dynamics of OSA tumors.
View Article and Find Full Text PDFAirway management in pediatric patients undergoing microvascular free tissue transfer reconstruction after mandibulectomy.
Int J Pediatr Otorhinolaryngol
December 2024
Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address:
Objectives: Microvascular free tissue transfer (MVFTT) for head and neck reconstruction is infrequently performed in pediatric patients. There is a paucity of data on perioperative airway management in pediatric MVFTT, such as the need for tracheostomy, which can pose higher morbidity to young patients due to potential long-term effects on the softer, more pliable laryngotracheal cartilage. Our objective was to report airway outcomes on pediatric patients undergoing MVFTT after segmental mandibulectomy with or without tracheostomy.
View Article and Find Full Text PDFMitochondria in skeletal system-related diseases.
Biomed Pharmacother
December 2024
Department of Orthopedics, First Hospital of China Medical University, No.155 Nanjing North Street, Shenyang, China.. Electronic address:
Skeletal system-related diseases, such as osteoporosis, arthritis, osteosarcoma and sarcopenia, are becoming major public health concerns. These diseases are characterized by insidious progression, which seriously threatens patients' health and quality of life. Early diagnosis and prevention in high-risk populations can effectively prevent the deterioration of these patients.
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