The authors examined the influence of the Bulgarian preparation Nivalin on the bioelectrical activity of practicaly healthy ureters of cats under the conditions of acute experiment. They used on the average 1,5--2 mg of Nivalin per kg of body weight as the whole amount was used singly and administered intravenously. They found that Nivalin caused the appearence of more frequent bioelectrical complexes of ureters, which in most cases was manifested in two phages--the first almost 1--15 minutes after the injection and the second-after 60--90 minutesmthere was also an improvement of the rhythm of the bioelectrical activity and amplitude changes in bioelectrical complexes. There was stabilization of the obtained effects around two hours after administration of Nivalin under the conditions of the experiment. The authors consider that in this direction the experiments should be continued and should be examined practicaly the therapeutic effect of Novalin on persons with disturbances in the dynamics of urinary pathways.
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Front Physiol
January 2025
Departamento de Paciente Crítico, Clínica Alemana de Santiago, Santiago, Chile.
Assessing muscle mass in critically ill patients remains challenging. This retrospective cohort study explores the potential of phase angle (PA°) derived from bioelectrical impedance analysis (BIA) as a surrogate marker for muscle mass monitoring by associating it with daily creatinine excretion (DCE), a structural and metabolic muscle mass marker. In 20 ICU patients, we observed a linear relationship between PA° and DCE at initial (S1) and follow-up (S2) points, with Rho values of 0.
View Article and Find Full Text PDFBMC Med Genomics
January 2025
Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Background: The growth in obesity and rates of abdominal obesity in developing countries is due to the dietary transition, meaning a shift from traditional, fiber-rich diets to Westernized diets high in processed foods, sugars, and unhealthy fats. Environmental changes, such as improving the quality of dietary fat consumed, may be useful in preventing or mitigating the obesity or unhealthy obesity phenotype in individuals with a genetic predisposition, although this has not yet been confirmed. Therefore, in this study, we investigated how dietary fat quality indices with metabolically healthy obesity (MHO) or metabolically unhealthy obesity (MUO) based on the Karelis criterion interact with genetic susceptibility in Iranian female adults.
View Article and Find Full Text PDFFront Med (Lausanne)
January 2025
Instituto de Medicina Fisica e Reabilitacao, IMREA, Hospital das Clínicas HCFMUSP, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil.
Background: Knee osteoarthritis (KOA) is the most common form of arthritis in adults and a leading cause of years lived with disability, representing a significant burden on healthcare worldwide.
Objective: Describe the structure and educational elements of the Knee-SCHOOL, a brief patient-centered multidisciplinary educational program for patients with KOA.
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Peptides
January 2025
College of Exercise and Health, Shenyang Sport University, Shenyang, Liaoning, PR China.
The neuropeptide phoenixin (PNX) may be involved in regulating the hypothalamic-pituitary-gonadal (HPG) axis and inflammatory responses. This study aims to investigate the role of PNX in the regulation of HPG axis function in ice hockey players and its impact on body composition. This cross-sectional study included 65 male ice hockey players aged 18-22, divided into untrained, non-elite athlete, and elite athlete groups.
View Article and Find Full Text PDFNat Mater
January 2025
Mechanisms of Morphogenesis Lab, Gulbenkian Institute of Science (IGC), Oeiras, Portugal.
Directed collective cell migration is essential for morphogenesis, and chemical, electrical, mechanical and topological features have been shown to guide cell migration in vitro. Here we provide in vivo evidence showing that endogenous electric fields drive the directed collective cell migration of an embryonic stem cell population-the cephalic neural crest of Xenopus laevis. We demonstrate that the voltage-sensitive phosphatase 1 is a key component of the molecular mechanism, enabling neural crest cells to specifically transduce electric fields into a directional cue in vivo.
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