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Changes in cerebrovascular reactivity as a marker of cognitive impairment risk: a transcranial Doppler study.
J Ultrasound
January 2025
Clinical Unit of Neurology, Department of Medicine, Surgery and Health Sciences, University Hospital and Health Services of Trieste, ASUGI, University of Trieste, Strada di Fiume, 447, 34149, Trieste, Italy.
Introduction: Post-stroke cognitive impairment (PSCI) and dementia affect short- and long-term outcome after stroke and can persist even after recover from a physical handicap. The process underlying PSCI is not yet fully understood. Transcranial Doppler ultrasound (TCD) is a feasible method to investigate cerebrovascular aging or dementia, through the pulsatility index (PI), the cerebrovascular reactivity (e.
View Article and Find Full Text PDFOptimizing TMS dosimetry: evaluating the effective electric field as a novel metric.
Phys Med Biol
January 2025
Department of Information Engineering, Electronics and Telecommunications (DIET) , University of Rome La Sapienza, Via Eudossiana 18, Rome, 00184, ITALY.
Objective: This study introduces the effective electric field (Eeff) as a novel observable for transcranial magnetic stimulation (TMS) numerical dosimetry. Eeff represents the electric field component aligned with the local orientation of cortical and white matter neuronal elements. To assess the utility of Eeff as a predictive measure for TMS outcomes, we evaluated its correlation with TMS induced muscle responses and compared it against conventional observables, including the electric (E-)field magnitude, and its components normal and tangential to the cortical surface.
View Article and Find Full Text PDFTranscranial direct current stimulation for patients with walking difficulties caused by cerebral small vessel disease: a randomized controlled study.
Front Aging Neurosci
January 2025
Department of Neurology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Introduction: Cerebral small vessel disease (CSVD) is a chronic systemic degenerative disease affecting small blood vessels in the brain, leading to cognitive impairments. Transcranial direct current stimulation (tDCS), a non-invasive brain stimulation technique that applies low electrical currents to the scalp, shows promise in treating cognitive and movement disorders. However, further clinical evaluation is required to assess the long-term effects of tDCS on neuroplasticity and gait in patients with CSVD.
View Article and Find Full Text PDFEvaluation of contralateral arterial flow compensation using transcranial Doppler in acute internal carotid artery occlusion and implications for neurological outcome.
Sci Rep
January 2025
Department of Neurology, Inner Mongolia Autonomous Region People's Hospital, Hohhot, China.
Acute internal carotid artery occlusion (AICAO) can result in malignant cerebral edema and unfavorable patient outcomes. This study evaluated the utility of transcranial Doppler (TCD) in assessing contralateral flow compensation and predicting outcomes in patients with AICAO. We enrolled 51 patients within 6 h of symptom onset and conducted TCD examinations to evaluate collateral circulation.
View Article and Find Full Text PDFImproving postsurgical paresis in brain tumor patients by transcranial magnetic stimulation.
J Neurooncol
January 2025
Department of Neurosurgery, School of Medicine, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany.
Background And Objectives: Recently, reduction of transcallosal inhibition by contralateral navigated repetitive transcranial magnetic stimulation (nrTMS) improved neurorehabilitation of glioma patients with new postoperative paresis. This multicentric study examines the effect of postoperative nrTMS in brain tumor patients to treat surgery-related upper extremity paresis.
Methods: This is a secondary analysis of two randomized and three one-arm studies in brain tumor patients with new/progressive postoperative paresis.
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