A fibrinous exudate developed in 8 children after cataract extraction. Blunt trauma was the cause of cataract formation in 6 children; the other 2 presented with congenital cataract. In 4 of 6 children with traumatic cataract, iris damage was evident. Seven children had an intraocular lens implanted. The development of fibrinous exudate in the anterior chamber was noted despite routine post-operative topically administered steroids. It typically formed 1-4 days after surgery. In all cases topical fortified steroids were unsuccessful in hastening dissolution. Intracameral injection of streptokinase (500-1000 IU) caused dissolution of fibrin in all cases. No adverse effects were apparent clinically with intraocular administration of streptokinase.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/eye.1996.74 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Didecyldimethylammonium chloride-induced lung fibrosis may be associated with phospholipidosis.
Toxicol Appl Pharmacol
December 2024
College of Medicine, Graduate School, Kyung Hee University, 02447, Republic of Korea; Human Health and Environmental Toxins Research Center, Kyung Hee University, 02447, Republic of Korea. Electronic address:
In the current study, we dosed didecyldimethylammonium chloride (DDAC) in mice by pharyngeal aspiration for 28 days or 90 days (weekly) and tried to elucidate the relationship between lamellar body formation and the lesions. When exposed for 28 days (0, 5, 10, 50, and 100 μg/head), all the mice in the 50 and 100 μg/head groups died since Day 2 after the third dosing (Day 16 after the first dosing). Edema, necrosis of bronchiolar and alveolar epithelium, and fibrinous exudate were observed in the lungs of all the dead mice, and chronic inflammatory lesions were observed in the lung tissues of alive mice.
View Article and Find Full Text PDFSubconjunctival trypsin injection for anterior chamber fibrin exudates in eyes with globe rupture following vitrectomy.
Int J Ophthalmol
November 2024
Department of Retina and Vitreous, Jingliang Eye Hospital, Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China.
Article Synopsis
- The study aimed to compare the safety and effectiveness of subconjunctival injections of trypsin versus dexamethasone (DEX) for treating fibrin exudates in patients after globe rupture repair.
- A total of 52 patients were treated with either trypsin or DEX, with results indicating that both treatments led to similar levels of exudate absorption, but trypsin had a quicker absorption time and was less irritating for patients.
- Overall, trypsin was found to be a more comfortable treatment option than DEX, with no adverse effects reported and stable intraocular pressure.
Emergence of highly virulent and multidrug-resistant in breeding sheep with pneumonia, Hainan Province, China.
Front Microbiol
October 2024
Lab of Microbiological Engineering (Infection and Immunity), School of Life and Health Sciences, Hainan Province Key Laboratory of One Health, Collaborative Innovation Center of One Health, Hainan University, Haikou, China.
Article Synopsis
- The article discusses a pneumonia outbreak in sheep in Hainan Island, which led to acute deaths during winter 2021-2022, highlighting the challenges of raising sheep in the region's tropical climate.
- Researchers conducted dissections and tests on six sheep, isolating a specific bacterial species responsible for the pneumonia, identified as multi-drug resistant with several virulence factors.
- The study concluded that the virulent bacteria were capable of causing serious health issues in both sheep and a mouse infection model, indicating potential zoonotic risks due to similarities with strains affecting humans and other animals.
Severe gastritis induced by pembrolizumab in metastatic vaginal cancer.
Gastrointest Endosc
October 2024
Gastroenterology Department, Portuguese Oncology Institute of Coimbra, Coimbra, Portugal.
A Severe Case of Infectious Necrotizing Anterior Scleritis Caused by after Vitreoretinal Surgery.
Case Rep Ophthalmol
September 2024
Department of Ophthalmology, Kindai University Faculty of Medicine, Osakasayama, Japan.
Introduction: This report describes a case of necrotizing scleritis caused by infection soon after vitreous surgery, which caused severe scleral melting and rapidly progressive necrosis that led to scleral perforation and bacterial endophthalmitis.
Case Presentation: The patient was an 86-year-old man with a history of type 2 diabetes mellitus who underwent pars plana vitrectomy (PPV) for vitreous hemorrhage in his right eye. On postoperative day 10, he complained of severe ocular pain and was found to have conjunctival edema and eyelid swelling, which was treated by topical and general systemic antibiotics.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!