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Neuropeptide Y in cancer-biological functions and potential clinical implications.
Cancer Metastasis Rev
January 2025
Department of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, BSB 231A, 3900 Reservoir Rd., NW, Washington, DC, 20057, USA.
Neuropeptide Y (NPY) is a sympathetic neurotransmitter widely distributed in the peripheral and central nervous system, affecting many physiological functions. Consequently, dysregulation of the NPY system contributes to numerous pathological disorders, including stress, obesity, and cancer. The pleiotropic functions of NPY in humans are mediated by G protein-coupled receptors (Y1R, Y2R, Y5R), which activate several signaling pathways and thereby regulate cell growth, differentiation, apoptosis, proliferation, angiogenesis, and metabolism.
View Article and Find Full Text PDFAcupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis.
J Vis Exp
December 2024
Integrated Chinese and Western Medicine Ear, Nose, Throat, Head, and Neck Surgery, Hospital of Chengdu University of Traditional Chinese Medicine;
Acupuncture Point Embedding Therapy is a comprehensive treatment method that combines modern biomaterials with acupuncture techniques. Acupoint catgut embedding (ACE) not only avoids the adverse reactions associated with Western medicine but also incorporates the benefits of traditional acupuncture, extending the duration of its therapeutic effects. Allergic rhinitis (AR) is a condition known for its challenging treatment and tendency to persist.
View Article and Find Full Text PDFUnveiling the Diverse Principles for Developing Sprayable Hydrogels for Biomedical Applications.
Biomacromolecules
January 2025
Center of Biomaterials, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Seoul 02792, Republic of Korea.
Sprayable hydrogels have emerged as a transformative innovation in biomedical technology, offering a versatile, efficient, and minimally invasive platform for various clinical applications. They form gels upon tissue contact, enabling seamless application on even complex surfaces. This property is especially useful in wound care, drug delivery, and tissue engineering, where localized and sustained release of therapeutics is essential.
View Article and Find Full Text PDFComparison of Overall and Domain-Specific Psychological Well-Being Between Homemakers and Employed Women: A Cross-Sectional Study From Perambalur District, Tamil Nadu.
Cureus
December 2024
Community Medicine, Dhanalakshmi Srinivasan Medical College and Hospital, Siruvachur, IND.
Background Women's psychological well-being (PWB) is influenced by various factors, including their occupational status and social roles. In India, where traditional and modern roles often intersect, understanding the PWB of homemakers and employed women is crucial for developing targeted mental health interventions. This study aimed to compare the overall and domain-specific PWB between homemakers and employed women in the Perambalur district, Tamil Nadu, using the 18-item Ryff's PWB Scale (PWBS).
View Article and Find Full Text PDFFoundational artificial intelligence models and modern medical practice.
BJR Artif Intell
January 2025
Machine and Hybrid Intelligence Lab, Department of Radiology, Northwestern University, Chicago, IL 60611, United States.
Our opinion piece pays homage to the evolution of medical practices, tracing back to the era of Hippocrates, through significant historical milestones, and drawing parallels with the principles underpinning foundational artificial intelligence (AI) models. It emphasizes the shared ethos of both domains: a commitment to comprehensive care that values diverse data integration and individualized patient treatment. The excitement surrounding foundation models in medical imaging is understandable.
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