A simple and sensitive (at the ng/mL level) method for buprenorphine assay in urine is described. Buprenorphine is extracted by a C18 cartridge, derivatized with dansyl chloride, resolved by a uni-dimensional, two developing mobile phase high-performance thin layer chromatography system and quantified by fluorescence densitometry at 340 nm.
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| http://dx.doi.org/10.1002/(SICI)1099-0801(199605)10:3<146::AID-BMC574>3.0.CO;2-A | DOI Listing |
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