Standard clinical protocols will allow busy physicians to meet the increasing demands made on them to evaluate and perform, if appropriate, in a given manner for a particular problem. When tracked, standard clinical protocols allow the demonstration that the right thing was done every time at the right time and place.
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Actionable Gene Alterations Identified in Patients With Malignant Melanoma by Targeted Sequencing in Japan.
JCO Precis Oncol
January 2025
Department of Medical Oncology, Hokkaido University Hospital, Sapporo, Hokkaido, Japan.
Purpose: Precision medicine plays an important role in the treatment of patients with advanced melanoma. Despite its high incidence in White patients, advanced melanoma is rare in Asian countries, hampering prospective clinical trials targeting the Asian population. This retrospective study aimed to elucidate the real-world molecular diagnoses and outcomes of Japanese patients with melanoma using comprehensive genome profiling (CGP).
View Article and Find Full Text PDFClinical and Radiographic Outcomes of Single-Unit Implant- Supported Restorations: A 12-Month Cross-Sectional Clinical Study.
Int J Oral Maxillofac Implants
January 2025
Purpose: This retrospective clinical study aims to analyze single-unit implant-supported restorations' clinical and radiographic outcomes comprehensively.
Materials And Methods: In this retrospective study, patients who had undergone 12 months of implant-supported singleunit fixed prosthetic treatment were scanned from the archives, and a hundred patients were included in the study. Implant success and survival rates were assessed according to the consensus decisions published at the International Oral Implantology Congress in 2007.
Retrospective evaluation of a novel ultrasound-based imaging analysis software for predicting radiofrequency ablation areas.
PLoS One
January 2025
Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Objective: This study aimed to introduce and evaluate a novel software-based system, BioTrace, designed for real-time monitoring of thermal ablation tissue damage during image-guided radiofrequency ablation for hepatocellular carcinoma (HCC).
Methods: BioTrace utilizes a proprietary algorithm to analyze the temporo-spatial behavior of thermal gas bubble activity during ablation, as seen in conventional B-mode ultrasound imaging. Its predictive accuracy was assessed by comparing the ablation zones it predicted with those annotated by radiologists using contrast-enhanced computed tomography (CECT) 24 hours post-treatment, considered the gold standard.
Introduction: Diagnosing dementia remains challenging in low-income settings due to limited diagnostic options and the absence of definitive biomarkers. The use of brain MRI in the diagnosis of dementia is infrequent in Uganda, and even when it is used, subtle findings like mild regional atrophy are often overlooked, despite being crucial for imaging diagnosis.
Objective: The purpose of this study was to explore the perceptions and practices of imaging personnel and physicians regarding the use of brain MRI as a diagnostic approach for dementia in Uganda.
Central venous pressure as a method of optimising atrio-ventricular delay after cardiac surgery.
PLoS One
January 2025
National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Introduction: Haemodynamic atrioventricular delay (AVD) optimisation has primarily focussed on signals that are not easy to acquire from a pacing system itself, such as invasive left ventricular catheterisation or arterial blood pressure (ABP). In this study, standard clinical central venous pressure (CVP) signals are tested as a potential alternative.
Methods: Sixteen patients with a temporary pacemaker after cardiac surgery were studied.
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