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Incidental detection of hereditary bisalbuminemia in a patient with positive DAT coombs: A case-based review.
Metabol Open
September 2024
Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, 11527, Athens, Greece.
Bisalbuminemia is a rare, typically benign condition marked by the presence of a bifid albumin band on serum protein electrophoresis. It can either be inherited due to a point mutation or acquired in association with various medical conditions, most commonly diabetes mellitus. Bisalbuminuria, the presence of bifid albumin in urine, may or may not accompany bisalbuminemia.
View Article and Find Full Text PDF[Familial bisalbuminemia].
Inn Med (Heidelb)
October 2024
Stauferklinikum Schwäbisch Gmünd, Mutlangen, Deutschland.
Bisalbuminemia is characterized by two albumin peaks in the electrophoresis of serum. There are different forms of bisalbuminemia: inherited and acquired. The acquired form is mainly transitory, whereas the familial form is permanent.
View Article and Find Full Text PDFBisalbuminemia.
Med Clin (Barc)
September 2024
Servicio de Medicina Interna, Hospital Universitario Virgen de las Nieves, Granada, España. Electronic address:
Bisalbuminemia: A Rare Incidental Finding in Monoclonal Gammopathy.
EJIFCC
December 2023
Consultant, department of Biochemistry, Basavatarakam Indo-American Cancer Hospital and Research Institute, Hyderabad, India.
Bisalbuminemia is a rare, benign, protein anomaly presenting with two distinct peaks of albumin on serum protein electrophoresis. It reflects the presence of a normal albumin and a modified albumin in the same individual. This condition can be either hereditary or acquired.
View Article and Find Full Text PDFCombined bisalbuminemia and Bisalbuminuria: A rare finding on serum and urine electrophoresis.
Clin Chim Acta
January 2024
Department of Pathology, University of Texas Medical Branch, Galveston, TX, United States. Electronic address:
Article Synopsis
- Bisalbuminemia and bisalbuminuria are rare conditions where abnormal albumin bands are found in serum and urine, typically discovered during screenings for other health issues, with a prevalence of 1 in 1,000 to 1 in 10,000.
- The reported case involved two adult male diabetic patients, one with rheumatoid arthritis and potential Sjogren syndrome, exhibiting both bisalbuminemia and bisalbuminuria, while the other had chronic kidney disease and exhibited bisalbuminemia only.
- These conditions may arise from genetic variants or be acquired, often associated with diabetes, and while many cases are harmless, some albumin variants can affect how the body handles certain hormones and medications, potentially leading to significant health
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