In the study the results of allergic investigations in 36 children with atopic eczema were demonstrated. Prick testing with 22 allergens made by Bencard and 5 natural allergens showed an allergic reaction in 28 children (77.8%). The positive reaction was noted more often in children with a generalized form of disease compared to a limited one (81.85 and 76.0% respectively). Allergy to inhalatory allergens was observed in 72.2%, to food allergens in 38.9% and to other allergens in 27.8% of patients. Among inhalatory allergens, sensitivity to domestic dust (55.6%), inhalatory allergens A1 and grass pollen (both 50.0%) and Dermatophagoides pt. (44.4%) were most common. Food allergens were represented by grain (16.7%), uncooked milk and chocolate (both 11.1%). The conducted investigations indicate, that uncooked or cooked milk and milk cream seem to be more accurate indicators of milk sensitivity than milk allergen by Bencard.
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World Allergy Organ J
May 2022
Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Health Science Center, Shenzhen University, No. 1066 Xueyuan Road, Nanshan District, Shenzhen 518060, China.
Background: House dust mites (HDMs) are the main source of indoor inhalatory allergens that cause IgE-mediated allergic diseases. The discovery and identification of HDM allergens are important for the diagnosis and treatment of allergic diseases.
Objective: We sought to identify a Group 39 (Der p) allergen, namely Der p 39, and explore its immunodominant IgE epitopes.
Auris Nasus Larynx
February 2022
Department of Clinical Immunology and Pulmology, General Hospital "Sveti Duh", Zagreb, Croatia.
Med Devices (Auckl)
March 2020
NanoRegMed Ltd, BioScience Innovation Centre, London, UK.
Introduction: Insufflation of powder hydroxypropylmethylcellulose (pHPMC) in the nose has been proven an effective barrier in subjects with rhinitis in many clinical studies. We conducted additionally in vitro and in vivo experiments to address outstanding efficacy and safety issues.
Methods: We used an experimental setup to demonstrate the inhibition of the diffusion of allergen extracts (house dust mite, Japanese cedar, Ragweed, Timothy grass) and pollutants (particulate matter 2.
PLoS One
April 2019
Laboratory of Molecular Biomedicine, Institute of Basic Biological Problems RAS, Pushchino, Russia Federation.
Purpose: House dust mites Dermatophagoides pteronyssinus are the main source of major inhalatory allergens inducing inflammatory response. Mite extract contain both allergenic proteins and lipopolysaccharides (LPS). The main allergenic protein, Der p 2, is a functional homolog of sMD-2, a protein providing blood cell response on LPS.
View Article and Find Full Text PDFAllergy Asthma Clin Immunol
October 2018
1Department and Clinic of Allergology, Clinical Immunology and Internal Diseases, Ludwik Rydygier Collegium Medicum in Bydgoszcz, NCU, Bydgoszcz, Poland.
Background: An allergy to mango is extremely rare. The antigenic composition of the fruit is not fully known. Profilin from mango has a structure similar to birch tree profiling: it is responsible for cross-reactions between mango and pear, apple, and peach.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!