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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1010241PMC
http://dx.doi.org/10.1136/ard.55.8.560DOI Listing

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Gastric antral vascular ectasia or "watermelon stomach" is a significant cause of nonvariceal upper GI bleeding and is characterized by red, tortuous ectatic vessels along longitudinal folds in the gastric antrum. The existing literature links GAVE to patients with cirrhosis, scleroderma, bone marrow transplantation, and chronic renal failure among other associations, but its pathophysiology remains ill-defined. Over 30 cases of hematopoietic stem cell transplant-related GAVE (HSCT-GAVE) have been reported in the literature to date and there are likely many more that go undiagnosed or are attributed to another cause of upper gastrointestinal bleeding.

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Gastric Antral Vascular Ectasia in Systemic Sclerosis: Current Concepts.

Int J Rheumatol

December 2015

School of Medicine, Universidad de los Andes, Bogota, Colombia ; Department of Rheumatology, Hospital Universitario Fundación Santa fe de Bogotá, Bogota, Colombia ; School of Medicine, Universidad Nacional de Colombia, Bogota, Colombia.

Introduction. Gastric antral vascular ectasia (GAVE) is a rare entity with unique endoscopic appearance described as "watermelon stomach." It has been associated with systemic sclerosis but the pathophysiological changes leading to GAVE have not been explained and still remain uncertain.

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Background: To date, there are no large studies on videocapsule endoscopy in systemic sclerosis (SSc). Consequently, the prevalence and features of gastrointestinal mucosal abnormalities in SSc have not been determined.

Aims: To determine both prevalence and characteristics of gastrointestinal mucosal abnormalities in unselected patients with SSc, using videocapsule endoscopy.

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