We report the case history of a 35-year-old male patient with lymphoblastic non-Hodgkin's lymphoma who acquired a systemic infection with Fusarium nygamai during the granulocytopenic phase of cytostatic treatment. The patient survived this infection after haematological recovery and treatment with intravenous amphotericin B (total dose 543 mg). Subsequent chemotherapy courses were not complicated by fungal infections. A recent trip to Egypt and severe chemotherapy-induced mucositis were probably the major causes of this severe infection.
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http://dx.doi.org/10.1111/j.1439-0507.1996.tb00113.x | DOI Listing |
Mol Biotechnol
December 2024
Department of Biotechnology, University of Mianwali, Punjab, 42200, Pakistan.
In Salmonella Typhimurium, efflux pump proteins, such as AcrD actively expel drugs and hazardous chemicals from bacterial cells, resulting in treatment failure and the emergence of antibiotic-resistant variants. Focusing on AcrD may lead to the development of novel antimicrobials against multidrug-resistant bacteria. However, challenges persist in achieving high selectivity, low toxicity, and effective bacterial penetration.
View Article and Find Full Text PDFFungal Biol
December 2024
Research National Council, Institute of Sciences of Food Production, CNR-ISPA, Via Amendola 122/O, 70126, Bari, Italy.
Maize is a worldwide crop yet can be associated with mycotoxigenic fungi, much investigated in humid tropical and cooler, wet temperate regions. However, in hot, arid/semi-arid regions data on their occurrence are poor. In this paper, we focused on interactions between maize and Fusarium fungal species in Tunisia, which has a Mediterranean climate, with hot, dry summers and milder, damper winters.
View Article and Find Full Text PDFJ Microbiol Biotechnol
May 2024
Moulay Ismail University of Meknès, Laboratory of Biotechnology and Bioresources Valorization, BP 11201, Zitoune Meknes City, Morocco.
Lignocellulolytic enzymes play a crucial role in efficiently converting lignocellulose into valuable platform molecules in various industries. However, they are limited by their production yields, costs, and stability. Consequently, their production by producers adapted to local environments and the choice of low-cost raw materials can address these limitations.
View Article and Find Full Text PDFBMC Microbiol
November 2023
Biochemistry Department, Faculty of Agriculture, Cairo University, Gamma St, Giza, 12613, Egypt.
Background: Exopolysaccharides (EPSs) produced by microbes are recognized as biomacromolecules of great significance. EPSs from fungi are widely used in a variety of biotechnological fields, including medicine, bioremediation, and agriculture.
Results: In this study, ten fungal isolates were isolated from Kafir El-Dair, Qalubia Governorate, Egypt.
Environ Sci Pollut Res Int
September 2023
Biological and Geological Sciences Department, Faculty of Education, Ain Shams University, Cairo, 11341, Egypt.
Green biosynthesized nanoparticles have a bright future because they can be produced using a method that is more energy-efficient, cost-effective, repeatable, and environmentally friendly than physical or chemical synthesis. In this study, silver nanoparticles (AgNPs) were produced using the Fusarium nygamai isolate AJTYC1. Several techniques were used to characterize the synthesized AgNPs, including UV-Vis spectroscopy, transmission electron microscope, zeta potential analysis, X-ray diffraction analysis, energy dispersive X-ray, and Fourier transform-infrared spectroscopy.
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