Synthesis and cytostatic activity of some sulfamido-anthraquinones.

Farmaco

Laboratorio de Química Farmacéutica, Facultad de Farmacia, Universidad de Santiago de Compostela, Spain.

Published: June 1996

N-1- or 2-anthraquinonyl derivatives of p-methyl-, p-methoxy- and p-aminobenzenesulfonamides were synthesized and evaluated in vitro as antitumour agents. Only N-(1-anthraquinonyl)-p-methylbenzenesulfonamide (1) and -p-methoxy benzene sulfonamide derivatives 3 and 4 showed slight antitumour activity.

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