The best method of screening for diabetic retinopathy is still debated: fundus photography, general practitioners, hospital physicians and ophthalmic opticians have been advocated. This study compared the performance of an ophthalmic optician with an ophthalmologist, both using mydriatic and slit lamp biomicroscopy and direct ophthalmoscopy. A total of 474 eyes of diabetics in a single group practice were examined by both practitioners at their annual check. There was total agreement about presence or absence of retinopathy in 366 eyes (77%). Although the optician diagnosed less background diabetic retinopathy (83 versus 123 eyes) and diabetic maculopathy (47 eyes versus 63 eyes), he would have referred 20 of 26 eyes with moderate or severe maculopathy and 33 of 36 eyes with moderate or severe background retinopathy: sensitivities of 0.77 and 0.92 respectively. This compares favourably with previous studies and we suggest that ophthalmic opticians with suitable training would be an effective body to screen for diabetic retinopathy.
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http://dx.doi.org/10.1038/eye.1996.18 | DOI Listing |
BMC Endocr Disord
January 2025
Dongzhimen Hospital, Affiliated to Beijing University of Chinese Medicine, Beijing, 100700, China.
Objective: To analyze the characteristics of pulmonary nodules (PNs) and related influencing factors in patients with type 2 diabetes mellitus (T2DM).
Methods: Retrospectively analyzed the clinical and biochemical characteristics of 224 patients with PNs and 488 patients with non-PNs in patients with T2DM, and compared the clinical data of 72 patients with large nodules (≥ 5 mm) and 152 patients with small nodules (< 5 mm) in the pulmonary nodules (PNs) group.
Results: Compared to the non-PNs group, the PNs Patients in the group had a longer duration of diabetes, higher age, serum creatinine (SCR), blood urea nitrogen (BUN) and the lower albumin (ALB) and body mass index (BMI); women, diabetic retinopathy (DR), diabetic peripheral neuropathy (DPN), and estimated glomerular filtration rate (eGFR) < 60 ml/min1.
BMC Ophthalmol
January 2025
Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221006, China.
Objective: This study aims to investigate the correlation between the development of diabetic retinopathy (DR) and the changes in corneal sub-basal nerve plexus (SNP) and corneal dendritic cells (DCs).
Methods: 58 patients with type 2 diabetes mellitus (T2DM) and 30 age- and sex-matched healthy participants underwent assessment of the corneal nerve. The DR group was divided into no diabetic retinopathy (NDR) and 29 eyes with mild to moderate non-proliferative diabetic retinopathy (NPDR).
Sci Rep
January 2025
Department of Networks and Cybersecurity, Hourani Center for Applied Scientific Research, Al-Ahliyya Amman University, Amman, Jordan.
Diabetic retinopathy stands as a leading cause of blindness among people. Manual examination of DR images is labor-intensive and prone to error. Existing methods to detect this disease often rely on handcrafted features which limit the adaptability and classification accuracy.
View Article and Find Full Text PDFAm J Ophthalmol
January 2025
Indian Health Outcomes, Public Health, and Economics Research Center, L V Prasad Eye Institute, Hyderabad, Telangana, India; Anant Bajaj Retina Institute, L V Prasad Eye Institute, Hyderabad, Telangana, India. Electronic address:
Purpose: To evaluate the safety and efficacy of fibrin glue in preventing early recurrence of vitreous haemorrhage following surgery for proliferative diabetic retinopathy (PDR).
Design: Single masked randomized-controlled clinical trial SUBJECTS: Consecutive patients with vitreous haemorrhage due to PDR undergoing primary vitreoretinal surgery were screened. After completing all vitreoretinal manoeuvres including endo-cautery to bleeders, infusion pressure was gradually reduced to 5 mmHg.
Life Sci
January 2025
Department of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, China; Department of Ophthalmology, Friendship Hospital of Ili Kazakh Autonomous Prefecture, Ili, China. Electronic address:
Aims: Diabetic retinopathy (DR) represents one of the most devastating sequences in patients with diabetes. Endothelial dysfunction is a key pathological feature and contributing factor to DR. In the present study we investigated the role of megakaryocytic leukemia 1 (MKL1) in DR pathogenesis.
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